Gastric neuroendocrine neoplasms (gNENs) display peculiar site-specific features among
all NENs. Their incidence and prevalence have been rising in the past few decades. gNENs …

Simple Summary This article discusses the use of peptide receptor radionuclide therapy
(PRRT) as a key treatment method for advanced, unresectable neuroendocrine tumors. It …

This ENETS guidance paper aims to provide practical advice to clinicians for the diagnosis,
treatment and follow‐up of functioning syndromes in pancreatic neuroendocrine tumours …

The aim of the present guidance paper was to update the previous ENETS guidelines on
well‐differentiated gastric and duodenal neuroendocrine tumours (NETs), providing …

High-grade neuroendocrine neoplasms are a rare disease entity and account for
approximately 10% of all neuroendocrine neoplasms. Because of their rarity, there is an …

This ENETS guidance paper, developed by a multidisciplinary working group, provides an
update on the previous colorectal guidance paper in a different format. Guided by key …

Background The optimal treatment for metastatic high-grade gastroenteropancreatic (GEP)
neuroendocrine neoplasms when Ki-67≤ 55% is unknown. A prospective multi-centre …

Background The prognosis for patients with poorly-differentiated extra-pulmonary
neuroendocrine carcinoma (PD-EP-NEC) is poor. A recognised first-line (1L) treatment for …

Gastric neuroendocrine tumors (G-NET) are rare tumors arising from enterochromaffin-like
cells of the gastric mucosa. They belong to a larger group called gastroenteropancreatic …

Simple Summary Neuroendocrine neoplasms (NENs) have a varied biology. While well-
differentiated neuroendocrine tumors (NETs) typically demonstrate indolent behavior, a …