[HTML][HTML] Abnormal tryptophan catabolism in diabetes mellitus and its complications: opportunities and challenges

J Gao, T Yang, B Song, X Ma, Y Ma, X Lin… - Biomedicine & …, 2023 - Elsevier
In recent years, the incidence rate of diabetes mellitus (DM), including type 1 diabetes
mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM) …

Understanding the role of hyperglycemia and the molecular mechanism associated with diabetic neuropathy and possible therapeutic strategies

M Kaur, S Mishra, P Swarnkar, P Patel, BD Kurmi… - Biochemical …, 2023 - Elsevier
Diabetic neuropathy is a neuro-degenerative disorder that encompasses numerous factors
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …

A mitochondrial nanoguard modulates redox homeostasis and bioenergy metabolism in diabetic peripheral neuropathy

Y Yao, X Lei, Y Wang, G Zhang, H Huang, Y Zhao… - ACS …, 2023 - ACS Publications
As a major late complication of diabetes, diabetic peripheral neuropathy (DPN) is the
primary reason for amputation. Nevertheless, there are no wonder drugs available …

Withametelin, a steroidal lactone, isolated from datura innoxa attenuates STZ-induced diabetic neuropathic pain in rats through inhibition of NF-kB/MAPK signaling

A Khan, B Shal, AU Khan, MW Baig, I Ul Haq… - Food and Chemical …, 2023 - Elsevier
Diabetic neuropathic pain is one of the microvascular complications of diabetes mellitus
characterized by symmetrical pain and sensory abnormalities. A steroidal lactone isolated …

[HTML][HTML] Advances in traditional Chinese medicine as adjuvant therapy for diabetic foot

FS Liu, Y Li, XS Guo, RC Liu, HY Zhang… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Diabetes mellitus (DM) is a complex disease that often causes multiple systemic
complications that have become a major international public health problem. Diabetic foot …

[HTML][HTML] Comparative Efficacy of East Asian Herbal Formulae Containing Astragali Radix–Cinnamomi Ramulus Herb-Pair against Diabetic Peripheral Neuropathy and …

HG Jo, E Baek, D Lee - Pharmaceutics, 2023 - mdpi.com
The Astragali Radix–Cinnamomi Ramulus herb-pair (ACP) has been widely used in the
treatment of diabetic peripheral neuropathy (DPN) as part of East Asian herbal medicine …

[HTML][HTML] Natural compounds efficacy in complicated diabetes: A new twist impacting ferroptosis

T Bao, X Zhang, W Xie, Y Wang, X Li, C Tang… - Biomedicine & …, 2023 - Elsevier
Ferroptosis, as a way of cell death, participates in the body's normal physiological and
pathological regulation. Recent studies have shown that ferroptosis may damage glucose …

[HTML][HTML] Effect of 10.6 μm laser moxibustion on inflammation in diabetic peripheral neuropathy rats

Y Yin, L Wang, L Zhao, L Lin, X Shen - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetic peripheral neuropathy (DPN) is the main cause of disability in diabetes patients but
the efficacy of available drugs is poor. Moxibustion is an adjunctive treatment for DPN that …

[HTML][HTML] Plasma exosomes improve peripheral neuropathy via miR-20b-3p/Stat3 in type I diabetic rats

J Li, G Wu, W Li, X Zhou, W Li, X Xu, K Xu… - Journal of …, 2023 - Springer
Background Diabetic peripheral neuropathy (DPN) is one of the most common
complications of diabetes and the main cause of non-traumatic amputation, with no ideal …

[HTML][HTML] Implication of lncRNA MSTRG. 81401 in Hippocampal Pyroptosis Induced by P2X7 Receptor in Type 2 Diabetic Rats with Neuropathic Pain Combined with …

T Zhan, S Tang, J Du, J Liu, B Yu, Y Yang… - International Journal of …, 2024 - mdpi.com
Major depressive disorder (MDD) is a common complication of diabetes and is often
observed alongside diabetic neuropathic pain (DNP) as a comorbidity in diabetic patients …