Recombinant antibodies are highly specific detection probes in research, diagnostics, and
have emerged over the last two decades as the fastest growing class of therapeutic proteins …

Secreted mammalian proteins require the development of robust protein over‐expression
systems for crystallographic and biophysical studies of protein function. Due to complex …

Viruses are ubiquitous in the environment. While many impart no deleterious effects on their
hosts, several are major pathogens. This risk of pathogenicity, alongside the fact that many …

Abstract Development of successful production strategies for recombinant proteins is a
challenging task due to problems associated with the scale‐up of bioprocesses. Recent …

During the past ten years, monoclonal antibodies (mAbs) have taken center stage in the field
of targeted therapy and diagnosis. This increased interest in mAbs is due to their binding …

Antifoams are often added to bioprocesses with little knowledge of their impact on the cells
or product. However, it is known that certain antifoams can affect the growth rates of both …

Currently, antibodies play major role in treating a wide variety of human diseases (eg,
cancer, viral infection, inflammation). Those pharmaceutic antibodies have become major …

Proteins are effective immunogens for generation of antibodies. However, occasionally the
native protein is known but not available for antibody production. In such cases synthetic …

During the last few decades, it has become evident that the compatibility of the yeast
biochemical environment with the ability to process and translate the RNA transcript, along …

Monoclonal antibodies (mAbs) are the fastest growing class of biopharmaceuticals reflecting
their diverse applications in research and the clinic. The correct glycosylation of mAbs is …