Macrophages as tools and targets in cancer therapy
A Mantovani, P Allavena, F Marchesi… - Nature Reviews Drug …, 2022 - nature.com
Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
Major pathways involved in macrophage polarization in cancer
C Kerneur, CE Cano, D Olive - Frontiers in immunology, 2022 - frontiersin.org
Macrophages play an important role in tissue homeostasis, tissue remodeling, immune
response, and progression of cancer. Consequently, macrophages exhibit significant …
response, and progression of cancer. Consequently, macrophages exhibit significant …
[HTML][HTML] Exosomes from TNF-α-treated human gingiva-derived MSCs enhance M2 macrophage polarization and inhibit periodontal bone loss
Mesenchymal stem cell (MSC)–derived exosome plays a central role in the cell-free
therapeutics involving MSCs and the contents can be customized under disease-associated …
therapeutics involving MSCs and the contents can be customized under disease-associated …
Polarized macrophages in periodontitis: characteristics, function, and molecular signaling
X Sun, J Gao, X Meng, X Lu, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Periodontitis (PD) is a common chronic infectious disease. The local inflammatory response
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …
miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …
Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19
SJ Theobald, A Simonis, T Georgomanolis… - EMBO molecular …, 2021 - embopress.org
Innate immunity triggers responsible for viral control or hyperinflammation in COVID‐19 are
largely unknown. Here we show that the SARS‐CoV‐2 spike protein (S‐protein) primes …
largely unknown. Here we show that the SARS‐CoV‐2 spike protein (S‐protein) primes …
Bone regeneration is mediated by macrophage extracellular vesicles
Multiple local and systemic factors including inflammation influence bone regeneration.
Several lines of evidence demonstrate that macrophages contribute to the immunological …
Several lines of evidence demonstrate that macrophages contribute to the immunological …
[HTML][HTML] Small extracellular vesicles derived from hypoxic preconditioned dental pulp stem cells ameliorate inflammatory osteolysis by modulating macrophage …
J Tian, W Chen, Y Xiong, Q Li, S Kong, M Li, C Pang… - Bioactive Materials, 2023 - Elsevier
Extensive macrophage inflammatory responses and osteoclast formation are predominant
during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small …
during inflammatory or infective osteolysis. Mesenchymal stem cell (MSC)-derived small …
Role of host and pathogen-derived microRNAs in immune regulation during infectious and inflammatory diseases
MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …
Mesenchymal stem cell-derived extracellular vesicles in liver immunity and therapy
R Wu, X Fan, Y Wang, M Shen, Y Zheng… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stem cells (MSCs), as the most common cell source for stem cell therapy, play
an important role in the modulation of innate and adaptive immune responses and have …
an important role in the modulation of innate and adaptive immune responses and have …