Predicting the evolution of syntenies—an algorithmic review

N El-Mabrouk - Algorithms, 2021 - mdpi.com
Syntenies are genomic segments of consecutive genes identified by a certain conservation
in gene content and order. The notion of conservation may vary from one definition to …

Evolution through segmental duplications and losses: a Super-Reconciliation approach

M Delabre, N El-Mabrouk, KT Huber, M Lafond… - Algorithms for Molecular …, 2020 - Springer
The classical gene and species tree reconciliation, used to infer the history of gene gain and
loss explaining the evolution of gene families, assumes an independent evolution for each …

Evolutionary history of the human multigene families reveals widespread gene duplications throughout the history of animals

N Pervaiz, N Shakeel, A Qasim, R Zehra… - BMC Evolutionary …, 2019 - Springer
Background The hypothesis that vertebrates have experienced two ancient, whole genome
duplications (WGDs) is of central interest to evolutionary biology and has been implicated in …

Phylogenomic analysis reveals ancient segmental duplications in the human genome

M Hafeez, M Shabbir, F Altaf, AA Abbasi - Molecular Phylogenetics and …, 2016 - Elsevier
Evolution of organismal complexity and origin of novelties during vertebrate history has
been widely explored in context of both regulation of gene expression and gene duplication …

Reconstructing the history of syntenies through super-reconciliation

M Delabre, N El-Mabrouk, KT Huber, M Lafond… - … , RECOMB-CG 2018 …, 2018 - Springer
Classical gene and species tree reconciliation, used to infer the history of gene gain and
loss explaining the evolution of gene families, assumes an independent evolution for each …

An insight into the evolutionary history of human MHC paralogon

R Naz, S Tahir, AA Abbasi - Molecular phylogenetics and evolution, 2017 - Elsevier
The vertebrate genome contains several closely spaced sets of paralogous genes from
distinct gene families on typically two, three or four different chromosomes (paralogons) …

Phylogenetic Analysis: GeneDuplicationandSpeciation

TR Singh, A Bansal - 2018 - ir.juit.ac.in
Significant progresshasbeenmadeinthepastfewdecade… theoryoftheoriginofspecies.
Different genomic methodshavehelpedtounderstandthegeneti… flow thatmakesnewspecies …

Functional conservation and divergence of duplicated fibroblast growth factor receptor 1 (fgfr1) genes in blunt snout bream (Megalobrama amblycephala)

QQ Zhang, FG Li, B Qin, J Chen, XY Jiang, SM Zou - Gene, 2015 - Elsevier
Fgfr1 is a fibroblast growth factor receptor involved in regulating cell growth, proliferation,
differentiation and migration. Here, we report the isolation and characterization of duplicated …

Computational Analysis of Rerep-Seq and Extrachromosomal Circular DNA

P Tatman - 2022 - search.proquest.com
Genomic amplifications are important in human evolution, physiology, and pathophysiology.
Rereplication is one mechanism that can produce site-specific amplifications. However …

Phylogenetic analyses of human 1/2/8/20 paralogons suggest segmental duplications during animal evolution

F Haq, U Saeed, R Khalid, M Qasim, M Mehmood - 3 Biotech, 2019 - Springer
Susumu Ohno hypothesized that the diversity of vertebrate gene families and genome is due
to two rounds of whole genome duplications (also referred as 2R hypothesis). The …