[HTML][HTML] Two centuries of vaccination: historical and conceptual approach and future perspectives
Over the past two centuries, vaccines have been critical for the prevention of infectious
diseases and are considered milestones in the medical and public health history. The World …
diseases and are considered milestones in the medical and public health history. The World …
[HTML][HTML] Potentials of saponins-based adjuvants for nasal vaccines
K Chen, N Wang, X Zhang, M Wang, Y Liu… - Frontiers in …, 2023 - frontiersin.org
Respiratory infections are a major public health concern caused by pathogens that colonize
and invade the respiratory mucosal surface. Nasal vaccines have the advantage of …
and invade the respiratory mucosal surface. Nasal vaccines have the advantage of …
[HTML][HTML] AZD1222-induced nasal antibody responses are shaped by prior SARS-CoV-2 infection and correlate with virologic outcomes in breakthrough infection
AA Aksyuk, H Bansal, D Wilkins, AM Stanley… - Cell Reports …, 2023 - cell.com
The nasal mucosa is an important initial site of host defense against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection. However, intramuscularly administered …
syndrome coronavirus 2 (SARS-CoV-2) infection. However, intramuscularly administered …
[HTML][HTML] Robust humoral and cellular recall responses to AZD1222 attenuate breakthrough SARS-CoV-2 infection compared to unvaccinated
J Maaske, S Sproule, AR Falsey… - Frontiers in …, 2023 - frontiersin.org
Background Breakthrough severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection in coronavirus disease 2019 (COVID-19) vaccinees typically produces milder …
infection in coronavirus disease 2019 (COVID-19) vaccinees typically produces milder …
[HTML][HTML] The bacterial spore as a mucosal vaccine delivery system
A Saggese, L Baccigalupi, G Donadio, E Ricca… - International Journal of …, 2023 - mdpi.com
The development of efficient mucosal vaccines is strongly dependent on the use of
appropriate vectors. Various biological systems or synthetic nanoparticles have been …
appropriate vectors. Various biological systems or synthetic nanoparticles have been …
[HTML][HTML] Oral mucosa immunity: ultimate strategy to stop spreading of pandemic viruses
H Jang, M Matsuoka, M Freire - Frontiers in Immunology, 2023 - frontiersin.org
Global pandemics are most likely initiated via zoonotic transmission to humans in which
respiratory viruses infect airways with relevance to mucosal systems. Out of the known …
respiratory viruses infect airways with relevance to mucosal systems. Out of the known …
[HTML][HTML] Research progress in the development of natural-product-based mucosal vaccine adjuvants
Y Gao, Y Guo - Frontiers in Immunology, 2023 - frontiersin.org
Mucosal vaccines have great potential and advantages in preventing infection caused by
multiple pathogens. In developing mucosal vaccines, the biggest challenge comes from …
multiple pathogens. In developing mucosal vaccines, the biggest challenge comes from …
[HTML][HTML] Investigation into the safety, and serological responses elicited by delivery of live intranasal vaccines for bovine herpes virus type 1, bovine respiratory …
A Flynn, C McAloon, K Sugrue, R Fitzgerald… - Frontiers in Veterinary …, 2024 - frontiersin.org
Despite the fact that pneumonia remains a leading cause of mortality and morbidity in pre-
weaned calves, relatively little is known regarding the effects of the concurrent …
weaned calves, relatively little is known regarding the effects of the concurrent …
Vaccine Strategies to Elicit Mucosal Immunity
Y Song, F Mehl, SL Zeichner - Vaccines, 2024 - mdpi.com
Vaccines are essential tools to prevent infection and control transmission of infectious
diseases that threaten public health. Most infectious agents enter their hosts across mucosal …
diseases that threaten public health. Most infectious agents enter their hosts across mucosal …
The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein
A Hammel, LM Cucos, I Caras… - Proceedings of the …, 2024 - National Acad Sciences
Microalgae are promising production platforms for the cost-effective production of
recombinant proteins. We have recently established that the red alga Porphyridium …
recombinant proteins. We have recently established that the red alga Porphyridium …