Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Current disease resistance breeding, which is largely dependent on the exploitation of
resistance genes in host plants, faces the serious challenges of rapidly evolving …

Abstract microbeMASST, a taxonomically informed mass spectrometry (MS) search tool,
tackles limited microbial metabolite annotation in untargeted metabolomics experiments …

Liquid chromatography-mass spectrometry (LC-MS) based untargeted metabolomics allows
to measure both known and unknown metabolites in the metabolome. However, unknown …

Studies of the human microbiome share both technical and conceptual similarities with
genome-wide association studies and genetic epidemiology. However, the microbiome has …

Label-free molecular imaging techniques such as matrix-assisted laser desorption ionization
mass spectrometry imaging (MALDI-MSI) enable the direct and simultaneous mapping of …

Humus formation of composting is crucial for improving organic fertilizer quality. Biochar has
been found to be a low-cost, eco-friendly and effective promoter for humus formation, while …

Background Icariin (ICA), an active ingredient extracted from Epimedium species, has
shown promising results in the treatment of Alzheimer's disease (AD), although its potential …

The utilization of microbial inoculants in the realm of sustainable agricultural and ecosystem
restoration has witnessed a surge in recent decades. This rise is largely attributed to …

Proteases are an evolutionarily conserved family of enzymes that degrade peptide bonds
and have been implicated in several common gastrointestinal (GI) diseases. Although …