MicroRNAs: history, biogenesis, and their evolving role in animal development and disease

M Bhaskaran, M Mohan - Veterinary pathology, 2014 - journals.sagepub.com
The discovery of microRNAs (miRNAs) in 1993 followed by developments and discoveries
in small RNA biology have redefined the biological landscape by significantly altering the …

MicroRNA regulatory networks in human adipose tissue and obesity

P Arner, A Kulyté - Nature Reviews Endocrinology, 2015 - nature.com
MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

Decreased mi R‐146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients 1 型糖尿病患者外周血 …

M Yang, L Ye, B Wang, J Gao, R Liu, J Hong… - Journal of …, 2015 - Wiley Online Library
摘要背景: 1 型糖尿病是一种常见的由自身免疫细胞介导的胰岛β 细胞受损的自身免疫性疾病.
研究表明microRNAs (miRNAs) 的异常表达可导致自身免疫性疾病的发生 …

Mesenchymal stem cell-derived extracellular vesicles as mediators of anti-inflammatory effects: endorsement of macrophage polarization

C Lo Sicco, D Reverberi, C Balbi, V Ulivi… - Stem cells …, 2017 - academic.oup.com
Abstract Mesenchymal Stem Cells (MSCs) are effective therapeutic agents enhancing the
repair of injured tissues mostly through their paracrine activity. Increasing evidences show …

Role of nuclear factor kappa B (NF-κB) signalling in neurodegenerative diseases: an mechanistic approach

S Singh, TG Singh - Current Neuropharmacology, 2020 - ingentaconnect.com
A transcriptional regulatory nuclear factor kappa B (NF-ΚB) protein is a modulator of cellular
biological activity via binding to a promoter region in the nucleus and transcribing various …

IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats

DI Chen, BJ Dixon, DM Doycheva, B Li… - Journal of …, 2018 - Springer
Background The endoplasmic reticulum (ER) is responsible for the control of correct protein
folding and protein function which is crucial for cell survival. However, under pathological …

Epigenetic mechanisms in inflammation

D Bayarsaihan - Journal of dental research, 2011 - journals.sagepub.com
Epigenetic modifications occur in response to environmental changes and play a
fundamental role in gene expression following environmental stimuli. Major epigenetic …

Micro rna s and bacterial infection

C Staedel, F Darfeuille - Cellular microbiology, 2013 - Wiley Online Library
Micro RNA s, small non‐coding RNAs expressed by eukaryotic cells, play pivotal roles in
shaping cell differentiation and organism development. Deregulated micro RNA expression …

MicroRNA expression profile in endometriosis: its relation to angiogenesis and fibrinolytic factors

A Braza-Boïls, J Marí-Alexandre, J Gilabert… - Human …, 2014 - academic.oup.com
Endometriosis, which is characterized by the presence of endometrial tissue (including
glands and stroma) in extra-uterine locations, is one of the most common benign …

Inhibition of house dust mite–induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment

A Collison, J Mattes, M Plank, PS Foster - Journal of Allergy and Clinical …, 2011 - Elsevier
Background Glucocorticoids are used as mainstay therapy for asthma, but some patients
remain resistant to therapy. MicroRNAs (miRNAs) are important regulators of the immune …