Menopause is the final step in the process referred to as ovarian ageing. The age related
decrease in follicle numbers dictates the onset of cycle irregularity and the final cessation of …

In humans and other mammalian species, the pool of resting primordial follicles serves as
the source of developing follicles and fertilizable ova for the entire length of female …

Context: The signals initiating growth of primordial follicles are unknown. Bone
morphogenetic protein 15 (BMP15) and growth differentiating factor 9 (GDF9) are promising …

During the last 2 decades, research on in vitro preantral follicle growth and oocyte
maturation has delivered fascinating advances concerning the knowledge of processes …

Purpose Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15)
play crucial roles in follicular development and oocyte maturation. This study aimed to …

Beyond the potential use of in vitro production of embryos (IVP) in breeding schemes,
embryos are also required for the establishment of new biotechnologies such as cloning and …

This study examined the influences of epidermal growth factor (EGF) and growth
differentiation factor 9 (GDF9) on in vitro viability and activation of primordial follicles in the …

The synergetic process of folliculogenesis is mainly regulated by GDF-9 and BMP-15 as well
as their receptors, such as BMPR2, TβR1 and BMPR1B. Expressions of these factors and …

Implementing ovarian tissue engineering for the maturation of primordial follicles, the most
abundant follicle population in the ovary, holds great potential for women fertility …

This study investigated effects of maternal overnutrition on gonadal development and
pituitary-gonadal gene expression in cattle fetuses at mid-and late-gestation. Twenty-seven …