Gene therapy leaves a vicious cycle

R Goswami, G Subramanian, L Silayeva… - Frontiers in …, 2019 - frontiersin.org
The human genetic code encrypted in thousands of genes holds the secret for synthesis of
proteins that drive all biological processes necessary for normal life and death. Though the …

[HTML][HTML] Viral and nonviral delivery systems for gene delivery

N Nayerossadat, T Maedeh, PA Ali - Advanced biomedical …, 2012 - journals.lww.com
Gene therapy is the process of introducing foreign genomic materials into host cells to elicit
a therapeutic benefit. Although initially the main focus of gene therapy was on special …

[图书][B] Principles and Practice of Sleep Medicine-E-Book: Expert Consult-Online and Print

MH Kryger, T Roth, WC Dement - 2010 - books.google.com
Principles and Practice of Sleep Medicine, 5th Edition, by Meir H. Kryger, MD, FRCPC,
Thomas Roth, PhD, and William C. Dement, MD, PhD, delivers the comprehensive …

Transgenic non-human animals capable of producing heterologous antibodies of various isotypes

N Lonberg, RM Kay - US Patent 5,569,825, 1996 - Google Patents
The invention relates to transgenic non-human animals capable of producing heterologous
antibodies of multiple isotypes. Heterologous antibodies are encoded by immuno globulin …

Transgenic non-human animals capable of producing heterologous antibodies

N Lonberg, RM Kay - US Patent 5,633,425, 1997 - Google Patents
OTHER PUBLICATIONS Rusconi et al. Nature 314: 330, 1985. Lorenz et al. NAR 15 (23):
9667, 1987. Nussenzweig et al. J. Exp. Med. 167: 1969, 1988. Goodhardt et al. PNAS 84 …

Transgenic non-human animals for producing heterologous antibodies

N Lonberg, RM Kay - US Patent 5,625,126, 1997 - Google Patents
US5625126A - Transgenic non-human animals for producing heterologous antibodies - Google
Patents US5625126A - Transgenic non-human animals for producing heterologous antibodies …

Transgenic non-human animals capable of producing heterologous antibodies of various isotypes

N Lonberg, RM Kay - US Patent 5,661,016, 1997 - Google Patents
The invention relates to transgenic non-human animals capable of producing heterologous
antibodies and transgenic non-human animals having inactivated endogenous …

Spermatogenesis following male germ-cell transplantation.

RL Brinster, JW Zimmermann - Proceedings of the National …, 1994 - National Acad Sciences
In the adult male, a population of diploid stem-cell spermatogonia continuously undergoes
self-renewal and produces progeny cells, which initiate the complex process of cellular …

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

C Lois, EJ Hong, S Pease, EJ Brown, D Baltimore - science, 2002 - science.org
Single-cell mouse embryos were infected in vitro with recombinant lentiviral vectors to
generate transgenic mice carrying the green fluorescent protein (GFP) gene driven by a …

Transgenic non-human animals capable of producing heterologous antibodies

N Lonberg, RM Kay - US Patent 5,770,429, 1998 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
24172033&utm_source= google_patent&utm_medium= platform_link&utm_campaign …