A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

Gut microbiota and its metabolites in depression: from pathogenesis to treatment

L Liu, H Wang, X Chen, Y Zhang, H Zhang, P Xie - EBioMedicine, 2023 - thelancet.com
Major depressive disorder is one of the most disabling mental disorders worldwide.
Increasing preclinical and clinical studies have highlighted that compositional and functional …

Faecalibacterium: a bacterial genus with promising human health applications

R Martín, D Rios-Covian, E Huillet… - FEMS Microbiology …, 2023 - academic.oup.com
In humans, many diseases are associated with alterations in gut microbiota, namely
increases or decreases in the abundance of specific bacterial groups. One example is the …

Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions

L Chang, Y Wei, K Hashimoto - Brain Research Bulletin, 2022 - Elsevier
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression

Z Li, J Lai, P Zhang, J Ding, J Jiang, C Liu… - Molecular …, 2022 - nature.com
The intricate processes of microbiota-gut-brain communication in modulating human
cognition and emotion, especially in the context of mood disorders, have remained elusive …

Maternal anxiety, depression and stress affects offspring gut microbiome diversity and bifidobacterial abundances

JD Galley, L Mashburn-Warren, LC Blalock… - Brain, Behavior, and …, 2023 - Elsevier
Uncovering mechanisms underlying fetal programming during pregnancy is of critical
importance. Atypical neurodevelopment during the pre-and immediate postnatal period has …

Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities

MA Ortega, MA Álvarez-Mon, C García-Montero… - Molecular …, 2023 - nature.com
Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Gut microbiota and psychiatric disorders: a two-sample Mendelian randomization study

JJ Ni, Q Xu, SS Yan, BX Han, H Zhang, XT Wei… - Frontiers in …, 2022 - frontiersin.org
Evidence supports the observational associations of gut microbiota with a variety of
psychiatric disorders, but the causal nature of such associations remains obscure. Aiming to …

The gut microbiome in depression and potential benefit of prebiotics, probiotics and synbiotics: a systematic review of clinical trials and observational studies

SR Alli, I Gorbovskaya, JCW Liu, NJ Kolla… - International journal of …, 2022 - mdpi.com
An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …