[HTML][HTML] The oxygen cascade from atmosphere to mitochondria as a tool to understand the (mal) adaptation to hypoxia

M Samaja, S Ottolenghi - International Journal of Molecular Sciences, 2023 - mdpi.com
Hypoxia is a life-threatening challenge for about 1% of the world population, as well as a
contributor to high morbidity and mortality scores in patients affected by various …

[HTML][HTML] Primary role of functional ischemia, quantitative evidence for the two-hit mechanism, and phosphodiesterase-5 inhibitor therapy in mouse muscular dystrophy

A Asai, N Sahani, M Kaneki, Y Ouchi, JAJ Martyn… - PloS one, 2007 - journals.plos.org
Background Duchenne Muscular Dystrophy (DMD) is characterized by increased muscle
damage and an abnormal blood flow after muscle contraction: the state of functional …

Vasomotion and flowmotion: physiological mechanisms and clinical evidence

M Intaglietta - Vascular Medicine Review, 1990 - journals.sagepub.com
The maintenance of adequate local tissue perfusion is the result of control mechanisms
which reside at the level of the microscopic blood vessels, and is produced by a single …

Continuous tissue oxygen tension measurement as a monitor of free-flap viability

MB Hirigoyen, KE Blackwell, WX Zhang… - Plastic and …, 1997 - journals.lww.com
Early recognition of vascular compromise within microvascular free-tissue transfers is
essential if reexploration is to prove successful. Tissue oxygen tension is increasingly …

Dependence of oxygen delivery on blood flow in rat brain: a 7 tesla nuclear magnetic resonance study

F Hyder, RP Kennan, I Kida, GF Mason… - Journal of Cerebral …, 2000 - journals.sagepub.com
Magnetic resonance imaging (MRI) and spectroscopy (MRS) were used at a magnetic field
strength of 7 T to measure CBF and CMRO2 in the sensorimotor cortex of mature rats at …

[HTML][HTML] Gradual not sudden change: multiple sites of functional transition across the microvascular bed

K Shaw, K Boyd, S Anderle… - Frontiers in Aging …, 2022 - frontiersin.org
In understanding the role of the neurovascular unit as both a biomarker and target for
disease interventions, it is vital to appreciate how the function of different components of this …

Effect of anemia on cardiac function, microvascular structure, and capillary hematocrit in rat hearts

K Rakusan, N Cicutti, F Kolar - American Journal of …, 2001 - journals.physiology.org
The effect of anemia on the coronary microcirculation was studied in young male rats.
Chronic anemia resulted in increased left ventricular end-diastolic pressure and decreased …

Calculations of intracapillary oxygen tension distributions in muscle

CD Eggleton, A Vadapalli, TK Roy, AS Popel - Mathematical biosciences, 2000 - Elsevier
Characterizing the resistances to O2 transport from the erythrocyte to the mitochondrion is
important to understanding potential transport limitations. A mathematical model is …

Blood and plasma viscosity and microvascular function in hemodilution

MC Mazzoni, AG Tsai… - European surgical …, 2002 - search.proquest.com
The efficacy of restoring of blood volume by means of colloidal solutions was established on
firm physiological basis when Messmer and co-workers [1] performed a series of pioneering …

Method for improving oxygen transport by stored red blood cells

TC Page, WR Light, EE Jacobs Jr - US Patent 6,811,778, 2004 - Google Patents
(57) ABSTRACT A method of treatment of a patient includes administering to the patient
Stored red blood cells and a hemoglobin Solution. The stored red blood cells and the …