Azoxy compounds are a distinctive group of bioactive secondary metabolites characterized
by a unique RN═ N+ (O–) R moiety. The azoxy moiety is present in various classes of …

Taxa of Buchnera aphidicola (hereafter “Buchnera”) are mutualistic intracellular symbionts of
aphids, known for their remarkable biological traits such as genome reduction, strand …

Over the past few decades, there has been a significant interest in the study of essential
genes, which are crucial for the survival of an organism under specific environmental …

Replication of Vibrio cholerae chromosome 2 (Chr2) initiates when the Chr1 locus, crtS (C
hr2 r eplication t riggering s ite) duplicates. The site binds the Chr2 initiator, RctB, and the …

Accurate identification of replication origins (ORIs) is crucial for a comprehensive
investigation into the progression of human cell growth and cancer therapy. Here, we …

Chitin is the second most abundant polysaccharide worldwide as part of arthropods'
exoskeletons and fungal cell walls. Low concentrations in soils and sediments indicate rapid …

The term microbe refers to the diverse spectrum of microscopic archaea, bacteria, protist,
fungi, and algae, of which some are beneficial, whereas others might be harmful. Being …

The proximity of genes to the origin of replication plays a key role in replication and
transcription-related processes in bacteria. Computational prediction of potential origin …

This thesis was part of the ChitoMat project, aiming to explore novel enzymes for chitin
conversion into tailored chitooligosaccharides. It led to the discovery of a novel chitinolytic …

Initiation of chromosomal replication requires dynamic nucleoprotein complexes. In most
eubacteria, the origin oriC contains multiple DnaA box sequences to which the ubiquitous …