Aging is an inevitable and multifactorial biological process. Free radicals have been
implicated in aging processes; it is hypothesized that they cause cumulative oxidative …

Intermittent fasting has grown in popularity over the past several years. However, intermittent
fasting has also been shown to relate to eating disorder behaviors and psychopathology, yet …

The main objective of this review is to provide an appraisal of the current status of the
relationship between energy intake and the life span of animals. The concept that a …

Understanding mechanisms of aging and determinants of life span will help to reduce age-
related morbidity and facilitate healthy aging. Average lifespan has increased over the last …

The prevalence of cardiovascular disease increases with advancing age. Although long-
term exposure to cardiovascular risk factors plays a major role in the etiopathogenesis of …

Brain aging is linked to certain types of neurodegenerative diseases and identifying new
therapeutic targets has become critical. Melatonin, a pineal hormone, associates with …

Advanced age is associated with a disproportionate prevalence of cardiovascular disease
(CVD). Intrinsic alterations in the heart and the vasculature occurring over the life course …

Background Parkinson's disease (PD) in elderly patients is the second most prevalent
neurodegenerative disease. The pathogenesis of PD is associated with dopaminergic …

Dietary restriction (DR) under laboratory conditions generally extends life span and delays
ageing across species as diverse as yeast, nematode worms, flies and mice, and is …

Elevated mammalian target of rapamycin (mTOR) signaling has been found in Alzheimer's
disease (AD) patients and is linked to diabetes and aging, two known risk factors for AD …