[HTML][HTML] Pericytes: The lung-forgotten cell type
AT Garrison, RE Bignold, X Wu, JR Johnson - Frontiers in physiology, 2023 - frontiersin.org
Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal
surface of microvessels, where they provide structural and biochemical support. Pericytes …
surface of microvessels, where they provide structural and biochemical support. Pericytes …
Pulmonary arterial hypertension: sex matters
JP Dignam, S Sharma, I Stasinopoulos… - British Journal of …, 2024 - Wiley Online Library
Pulmonary arterial hypertension (PAH) is a complex disease of multifactorial origin. While
registries have demonstrated that women are more susceptible to the disease, females with …
registries have demonstrated that women are more susceptible to the disease, females with …
[HTML][HTML] Dapagliflozin reduces the vulnerability of rats with pulmonary arterial hypertension-induced right heart failure to ventricular arrhythmia by restoring calcium …
Background Malignant ventricular arrhythmia (VA) is a major contributor to sudden cardiac
death (SCD) in patients with pulmonary arterial hypertension (PAH)-induced right heart …
death (SCD) in patients with pulmonary arterial hypertension (PAH)-induced right heart …
[HTML][HTML] Cannabidiol alleviates right ventricular fibrosis by inhibiting the transforming growth factor β pathway in monocrotaline-induced pulmonary hypertension in …
A Krzyżewska, M Baranowska-Kuczko… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Cannabidiol (CBD) is a non-intoxicating compound of Cannabis with anti-fibrotic properties.
Pulmonary hypertension (PH) is a disease that can lead to right ventricular (RV) failure and …
Pulmonary hypertension (PH) is a disease that can lead to right ventricular (RV) failure and …
[HTML][HTML] Cannabidiol improves antioxidant capacity and reduces inflammation in the lungs of rats with monocrotaline-induced pulmonary hypertension
A Krzyżewska, M Baranowska-Kuczko, A Jastrząb… - Molecules, 2022 - mdpi.com
Cannabidiol (CBD) is a plant-derived compound with antioxidant and anti-inflammatory
properties. Pulmonary hypertension (PH) is still an incurable disease. CBD has been …
properties. Pulmonary hypertension (PH) is still an incurable disease. CBD has been …
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension
AM Santamans, B Cicuéndez, A Mora… - Science …, 2024 - science.org
Pulmonary hypertension (PH) can affect both pulmonary arterial tree and cardiac function,
often leading to right heart failure and death. Despite the urgency, the lack of understanding …
often leading to right heart failure and death. Despite the urgency, the lack of understanding …
[HTML][HTML] Alleviating experimental pulmonary hypertension via co-delivering FoxO1 stimulus and apoptosis activator to hyperproliferating pulmonary arteries
B Li, C Teng, H Yu, X Jiang, X Xing, Q Jiang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Pulmonary hypertension (PH) is an insidious pulmonary vasculopathy with high mortality
and morbidity and its underlying pathogenesis is still poorly delineated. The …
and morbidity and its underlying pathogenesis is still poorly delineated. The …
[HTML][HTML] Ntsr1 contributes to pulmonary hypertension by enhancing endoplasmic reticulum stress via JAK2-STAT3-Thbs1 signaling
ZX Wei, XX Cai, YD Fei, Q Wang, XL Hu, C Li… - Translational …, 2024 - Elsevier
Pulmonary hypertension (PH) is a severe clinical syndrome with pulmonary vascular
remodeling and poor long-term prognosis. Neurotensin receptor 1 (Ntsr1), serve as one of …
remodeling and poor long-term prognosis. Neurotensin receptor 1 (Ntsr1), serve as one of …
[HTML][HTML] Novel insights and new therapeutic potentials for macrophages in pulmonary hypertension
Y Zuo, B Li, M Gao, R Xiong, R He, N Li, Q Geng - Respiratory Research, 2024 - Springer
Inflammation and immune processes underlie pulmonary hypertension progression. Two
main different activated phenotypes of macrophages, classically activated M1 macrophages …
main different activated phenotypes of macrophages, classically activated M1 macrophages …