Short-chain fatty acid metabolism and multiple effects on cardiovascular diseases
T Hu, Q Wu, Q Yao, K Jiang, J Yu, Q Tang - Ageing research reviews, 2022 - Elsevier
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, and fatty acid
metabolism has been well studied. Short-chain fatty acids (SCFAs) have been less …
metabolism has been well studied. Short-chain fatty acids (SCFAs) have been less …
Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications
H Zhang, K Yang, F Chen, Q Liu, J Ni, W Cao… - Frontiers in …, 2022 - frontiersin.org
The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …
special attention because of its function in the development and progression of …
Fibrin clot properties in cardiovascular disease: from basic mechanisms to clinical practice
M Ząbczyk, RAS Ariëns, A Undas - Cardiovascular research, 2023 - academic.oup.com
Fibrinogen conversion into insoluble fibrin and the formation of a stable clot is the final step
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …
of the coagulation cascade. Fibrin clot porosity and its susceptibility to plasmin-mediated …
The role of aldehyde dehydrogenase 2 in cardiovascular disease
J Zhang, Y Guo, X Zhao, J Pang, C Pan… - Nature Reviews …, 2023 - nature.com
Abstract Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the
detoxification of alcohol-derived acetaldehyde and endogenous aldehydes. The inactivating …
detoxification of alcohol-derived acetaldehyde and endogenous aldehydes. The inactivating …
Obesity phenotypes and cardiovascular risk: from pathophysiology to clinical management
Obesity epidemic reached the dimensions of a real global health crisis with more than one
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
billion people worldwide living with obesity. Multiple obesity-related mechanisms cause …
Dietary inflammatory potential and biological aging among US adults: a population-based study
R Xie, Z Ning, M Xiao, L Li, M Liu, Y Zhang - Aging clinical and …, 2023 - Springer
Objectives The rate of biological aging is influenced by various factors such as genetics,
environment, and diet. The dietary inflammatory index (DII) is strongly associated with …
environment, and diet. The dietary inflammatory index (DII) is strongly associated with …
[HTML][HTML] SIRT1 and SIRT6: The role in aging-related diseases
Y You, W Liang - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2023 - Elsevier
Aging is characterized by progressive functional deterioration with increased risk of
mortality. It is a complex biological process driven by a multitude of intertwined mechanisms …
mortality. It is a complex biological process driven by a multitude of intertwined mechanisms …
Sirtuin 2 deficiency aggravates ageing-induced vascular remodelling in humans and mice
Aims The mechanisms underlying ageing-induced vascular remodelling remain unclear.
This study investigates the role and underlying mechanisms of the cytoplasmic deacetylase …
This study investigates the role and underlying mechanisms of the cytoplasmic deacetylase …
Circadian regulation in aging: Implications for spaceflight and life on earth
Alterations in the circadian system are characteristic of aging on Earth. With the decline in
physiological processes due to aging, several health concerns including vision loss …
physiological processes due to aging, several health concerns including vision loss …
Role of inflammation in cardiac remodeling after acute myocardial infarction
FA Fonseca, MC Izar - Frontiers in physiology, 2022 - frontiersin.org
Atherosclerosis is defined as an inflammatory disease. Low-grade inflammation is present in
all phases of the cardiovascular continuum, since the establishment of cardiovascular risk …
all phases of the cardiovascular continuum, since the establishment of cardiovascular risk …