Short chain fatty acids: microbial metabolites for gut-brain axis signalling
KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …
prominence in recent years. Understanding the relationship between the gut microbiota, the …
Microbiota-derived metabolites as drivers of gut–brain communication
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …
Multi-level analysis of the gut–brain axis shows autism spectrum disorder-associated molecular and microbial profiles
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
heterogeneous cognitive, behavioral and communication impairments. Disruption of the gut …
[HTML][HTML] Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …
disruption of their integrity contributes to local and gut-distal pathologies. Yet, the …
Early-life differences in the gut microbiota composition and functionality of infants at elevated likelihood of developing autism spectrum disorder
S Zuffa, P Schimmel, A Gonzalez-Santana… - Translational …, 2023 - nature.com
Evidence from cross-sectional human studies, and preliminary microbial-based intervention
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …
studies, have implicated the microbiota-gut-brain axis in the neurobiology of autism …
Safety and target engagement of an oral small-molecule sequestrant in adolescents with autism spectrum disorder: an open-label phase 1b/2a trial
A Stewart Campbell, BD Needham, CR Meyer, J Tan… - Nature medicine, 2022 - nature.com
Autism spectrum disorder (ASD) is defined by hallmark behaviors involving reduced
communication and social interaction as well as repetitive activities and restricted interests …
communication and social interaction as well as repetitive activities and restricted interests …
Shedding light on biological sex differences and microbiota–gut–brain axis: a comprehensive review of its roles in neuropsychiatric disorders
Women and men are suggested to have differences in vulnerability to neuropsychiatric
disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD) …
disorders, including major depressive disorder (MDD), generalized anxiety disorder (GAD) …
Understanding the role of the gut microbiome in brain development and its association with neurodevelopmental psychiatric disorders
The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …
nervous system. During fetal development, the initial colonization of the microbiome …
The microbiota and the gut–liver axis in primary sclerosing cholangitis
JR Hov, TH Karlsen - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …
owing to the close association between liver disease and colonic inflammation. It is well …
Maternal inflammation and its ramifications on fetal neurodevelopment
Exposure to heightened inflammation in pregnancy caused by infections or other
inflammatory insults has been associated with the onset of neurodevelopmental and …
inflammatory insults has been associated with the onset of neurodevelopmental and …