In women, the non-growing population of follicles that comprise the ovarian reserve is
determined at birth and serves as the reservoir for future fertility. This reserve of dormant …

Primary ovarian insufficiency (POI) is a rare gynecological condition. This disease causes
menstrual disturbances, infertility, and various health problems. Historically, hormone …

Primordial follicles are the starting point of follicular development and the basic functional
unit of female reproduction. Primordial follicles are formed around birth, and most of the …

Development of early follicles, especially the activation of primordial follicles, is strictly
modulated by a network of signaling pathways. Recent advance in ovarian physiology has …

In brief Ovarian tissue cryopreservation and culture provide an option for fertility preservation
without tissue grafting, but need optimization. This study reveals that vitrified bovine ovarian …

Fertility preservation has received unprecedented attention nowadays. In addition to
cryopreservation and re-implantation of embryos, oocytes, and ovarian tissue pieces, in vitro …

In recent years, ovarian tissue cryopreservation has rapidly developed as a successful
method for preserving the fertility of girls and young women with cancer or benign conditions …

In vitro ovarian cortical tissue culture, followed by culture of isolated secondary follicles, is a
promising future option for production of mature oocytes. Although efforts have been made …

The aims of the present study were to evaluate the protective effects of rutin during cisplatin-
induced ovarian toxicity in mice and to verify the possible involvement of the phosphatase …

Understanding and control of the massive and accelerated follicular growth that occurs
during in vitro culture of ovarian tissue is a crucial step toward the development of efficient …