Global prevalence and incidence of tinnitus: a systematic review and meta-analysis

CM Jarach, A Lugo, M Scala, PA van den Brandt… - JAMA …, 2022 - jamanetwork.com
Importance To date, no systematic review has taken a meta-analytic approach to estimating
the prevalence and incidence of tinnitus in the general population. Objective To provide …

Low evidence for tinnitus risk factors: A systematic review and meta-analysis

R Biswas, E Genitsaridi, N Trpchevska, A Lugo… - Journal of the …, 2023 - Springer
Abstract Aims/Hypothesis Identifying risk factors for tinnitus could facilitate not only the
recommendations for prevention measures, but also identifying potential pathways for new …

Alterations in auditory brain stem response distinguish occasional and constant tinnitus

NK Edvall, G Mehraei, M Claeson… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND The heterogeneity of tinnitus is thought to underlie the lack of objective
diagnostic measures. METHODS Longitudinal data from 20,349 participants of the Swedish …

A genome-wide association study of tinnitus reveals shared genetic links to neuropsychiatric disorders

IS Bhatt, N Wilson, R Dias, A Torkamani - Scientific reports, 2022 - nature.com
Tinnitus, a phantom perception of sound in the absence of any external sound source, is a
prevalent health condition often accompanied by psychiatric comorbidities. Recent genome …

Pilot study evaluating everolimus molecular mechanisms in tuberous sclerosis complex and focal cortical dysplasia

DF Leitner, E Kanshin, M Askenazi, Y Siu, D Friedman… - Plos one, 2022 - journals.plos.org
Background Tuberous sclerosis complex (TSC) and some focal cortical dysplasias (FCDs)
are associated with dysfunctional mTOR signaling, resulting in increased cell growth and …

Using coding and non-coding rare variants to target candidate genes in patients with severe tinnitus

A Gallego-Martinez, A Escalera-Balsera… - npj Genomic …, 2022 - nature.com
Tinnitus is the phantom percept of an internal non-verbal set of noises and tones. It is
reported by 15% of the population and it is usually associated with hearing and/or brain …

A Systematic Review on the Genetic Contribution to Tinnitus

P Perez-Carpena, JA Lopez-Escamez… - Journal of the …, 2024 - Springer
Purpose To assess the available evidence to support a genetic contribution and define the
role of common and rare variants in tinnitus. Methods After a systematic search and quality …

Unification of Treatments and Interventions for Tinnitus Patients (UNITI): a study protocol for a multi-center randomized clinical trial

S Schoisswohl, B Langguth, M Schecklmann… - Trials, 2021 - Springer
Background Tinnitus represents a relatively common condition in the global population
accompanied by various comorbidities and severe burden in many cases. Nevertheless …

Current and emerging therapies for chronic subjective tinnitus

KW Park, P Kullar, C Malhotra… - Journal of Clinical …, 2023 - mdpi.com
Importance: Chronic subjective tinnitus, the perception of sound without an external source
for longer than six months, may be a greatly debilitating condition for some people, and is …

Rare deletions or large duplications contribute to genetic variation in patients with severe tinnitus and Meniere disease

A Escalera-Balsera, AM Parra-Perez… - Genes, 2023 - mdpi.com
Meniere disease (MD) is a debilitating disorder of the inner ear defined by sensorineural
hearing loss (SNHL) associated with episodes of vertigo and tinnitus. Severe tinnitus, which …