Multitarget drug design strategy: quinone–tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects
E Nepovimova, E Uliassi, J Korabecny… - Journal of medicinal …, 2014 - ACS Publications
We report the identification of multitarget anti-Alzheimer compounds designed by combining
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
Multitarget Drug Design Strategy: Quinone Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects
E Nepovimova, C Bergamini, R Fato… - Journal of Medicinal …, 2014 - hero.epa.gov
We report the identification of multitarget anti-Alzheimer compounds designed by combining
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects
E Nepovimova, E Uliassi, J Korabecny… - JOURNAL OF …, 2014 - cris.unibo.it
We report the identification of multitarget anti-Alzheimer compounds designed by combining
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects.
E Nepovimova, E Uliassi, J Korabecny… - Journal of Medicinal …, 2014 - europepmc.org
We report the identification of multitarget anti-Alzheimer compounds designed by combining
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
Multitarget drug design strategy: quinone-tacrine hybrids designed to block amyloid-β aggregation and to exert anticholinesterase and antioxidant effects
E Nepovimova, E Uliassi… - Journal of …, 2014 - pubmed.ncbi.nlm.nih.gov
We report the identification of multitarget anti-Alzheimer compounds designed by combining
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …
a naphthoquinone function and a tacrine fragment. In vitro, 15 compounds displayed …