Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde… - Proceedings of the …, 2019 - National Acad Sciences
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde… - … of the National …, 2019 - researchexperts.utmb.edu
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde, NF Liachko, H Wang… - 2019 - repositorio-indicasat.org.pa
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde, NF Liachko… - Proceedings of the …, 2019 - cir.nii.ac.jp
抄録< jats: title> Significance</jats: title>< jats: p> Amyotrophic lateral sclerosis (ALS) is a
devastating, motor neuron degenerative disease without any cure to date. About 95% of ALS …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.

J Mitra, EN Guerrero, PM Hegde… - Proceedings of the …, 2019 - europepmc.org
Results TDP-43 Is a Component of the DDR Signaling for DSB Repair. Following up on a
proteomic analysis by Taylor and coworkers (15), which showed the NHEJ-initiating DSB …

[PDF][PDF] Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitraa, EN Guerreroa, PM Hegdea, NF Liachkod… - researchgate.net
Results TDP-43 Is a Component of the DDR Signaling for DSB Repair. Following up on a
proteomic analysis by Taylor and coworkers (15), which showed the NHEJ-initiating DSB …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde… - Proceedings of the …, 2019 - pubmed.ncbi.nlm.nih.gov
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde, NF Liachko… - Proceedings of the …, 2019 - JSTOR
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects

J Mitra, EN Guerrero, PM Hegde, NF Liachko, H Wang… - 2019 - repositorio-indicasat.org.pa
Genome damage and their defective repair have been etiologically linked to degenerating
neurons in many subtypes of amyotrophic lateral sclerosis (ALS) patients; however, the …

Motor Neuron Disease-Associated Loss of Nuclear TDP-43 Is Linked to DNA Double-Strand Break Repair Defects

J Mitra, EN Guerrero, PM Hegde, NF Liachko… - 2018 - papers.ssrn.com
Loss of nuclear TDP-43 has been linked to amyotrophic lateral sclerosis (ALS), which also
features increased genome damage in affected neurons. Although TDP-43 binds to DNA, its …