Metastasis is a complex process that involved in various genetic and epigenetic alterations
during the progression of breast cancer. Recent evidences have indicated that the mutation …

Thanks to the advancement in science and technology and a significant number of cancer
research programs being carried out throughout the world, the prevention, prognosis and …

Epigenetic alterations are heritable changes in gene expression that occur without causing
any change in DNA sequence. They are important key factors for cancer development and …

Breast carcinogenesis involves genetic and epigenetic alterations that cause aberrant gene
function. Recent progress in the knowledge of epigenomics has had a profound impact on …

Background Epigenetic regulation has emerged to be the critical steps for tumorigenesis
and metastasis. Multiple histone methyltransferase and demethylase have been implicated …

Background Dysregulation of the epigenome is a common event in malignancy; however,
deciphering the earliest cancer-associated epigenetic events remains a challenge. Cancer …

Background Epigenetic regulators are frequently mutated or aberrantly expressed in a
variety of cancers, leading to altered transcription states that result in changes in cell identity …

The onset and progression of breast cancer are linked to genetic and epigenetic changes
that alter the normal programming of cells. Epigenetic modifications of DNA and histones …

Epigenetic changes are critical for development and progression of cancers, including
breast cancer. Significant progress has been made in the basic understanding of how …

Breast cancer remains a common cause of cancer-related death in women. Therefore,
further studies are necessary for the comprehension of breast cancer and the revolution of …