… to activate downstream signaling events. TRAF-dependent … of human diseases such as
cancers and autoimmune diseases, … TRAF molecules in signaling and in human diseases. …

… immune system on human diseases. In particular, the role of the molecules that initiate
and amplify innate immune pathways, namely damage-associated molecular patterns (DAMPs), …

… Most human diseases are related in some way to the loss or … are gaining new perspectives
in human diseases related to gene … Complex human diseases such as cancer and type 2 …

… Reference was made to the fact that loss of XLF/Cernunnos causes a new human
disease, characterized by radiosensitivity and severe-combined immune-deficiency. …

… has had on our understanding of the mechanistic basis of human disease, revealing critical
roles … , working together, continue to unravel the molecular basis of diverse human disorders. …

… and, more recently, several human diseases have been recognized due to … molecular
features, biological functions of WD-repeat proteins, and their association with human disease…

… molecular events that precipitate disease have begun to be understood. Protein aggregation
is a common feature of many neurodegenerative diseases, … In this process, one molecule (…

… pathophysiology as a novel mechanism of human disease. … This article will review some
of the basic molecular … of human disease attributable to mutations in mRNA regulatory sites. …

… in disease pathogenesis. To use an analogy regarding our current knowledge about the
molecular events … Nonetheless, we certainly have a better grasp of the pathogenic events …

… into the dynamic molecular events occurring during the process of DSB repair in human cells.
… use of this assay will uncover many more molecular details involved with DSB responses. …