circCIMT Silencing Promotes Cadmium‐Induced Malignant Transformation of Lung Epithelial Cells Through the DNA Base Excision Repair Pathway

M Li, W Chen, J Cui, Q Lin, Y Liu, H Zeng… - Advanced …, 2023 - Wiley Online Library
Abstract Changes in gene expression in lung epithelial cells are detected in cancer tissues
during exposure to pollutants, highlighting the importance of gene‐environmental …

CircSPAG16 suppresses cadmium‐induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt

Q Wang, S Pan, Q Jiang, L Li, W Tu… - Molecular …, 2021 - Wiley Online Library
Circular RNAs (circRNAs) have been implicated to have important regulatory functions in
chemical carcinogenesis via sponging microRNAs to regulate gene expression. Our study …

Circular RNA circ_Cabin1 promotes DNA damage in multiple mouse organs via inhibition of non-homologous end-joining repair upon PM2.5 exposure

H Zeng, M Li, Q Hua, Y Liu, Y Shao, Q Diao, Y Ling… - Archives of …, 2021 - Springer
Abstract Fine particulate matter (PM2. 5) has been shown to induce DNA damage. Circular
RNAs (circRNAs) have been implicated in various disease processes related to …

[HTML][HTML] The pivotal regulatory factor circBRWD1 inhibits arsenic exposure-induced lung cancer occurrence by binding mRNA and regulating its stability

X Li, S Chen, X Wang, R Zhang, J Yang, H Xu… - Molecular Therapy …, 2022 - cell.com
Multiple studies have indicated that circular RNAs (circRNAs) play a regulatory role in
different stages of tumors by interacting with various molecules. With continuous in-depth …

[HTML][HTML] DNMT3A-mediated high expression of circ_0057504 promotes benzo [a] pyrene-induced DNA damage via the NONO-SFPQ complex in human bronchial …

M Qiu, N Zhang, S Yao, H Zhou, X Chen, Y Jia… - Environment …, 2022 - Elsevier
Abstract Benzo [a] pyrene (B [a] P) is a class I carcinogen and hazardous environmental
pollutant with genetic toxicity. Understanding the molecular mechanisms underlying genetic …

Circ_0089282 inhibits carbon black nanoparticle-induced DNA damage by promoting DNA repair protein in the lung

H Zhang, H Zhou, N Zhang, Y Jia, M Qiu… - Toxicological …, 2023 - academic.oup.com
Inhalation of carbon black nanoparticles (CBNPs) can impair lung tissue and cause DNA
damage, but the epigenetic mechanism responsible for these effects is still unclear. We …

[HTML][HTML] Circ-SHPRH suppresses cadmium-induced transformation of human bronchial epithelial cells by regulating QKI expression via miR-224–5p

M Zhou, L Li, B Chen, S Pan, W Tu, Y Hou… - Ecotoxicology and …, 2021 - Elsevier
Circular RNAs (circRNAs) have been demonstrated to play critical roles in the pathogenesis
of human cancers and carcinogenesis of several environmental pollutants. Nevertheless …

circCCND1 regulates oxidative stress and FGF9 to enhance chemoresistance of non-small cell lung cancer via sponging miR-187-3p

J Geng, K Yang - DNA and Cell Biology, 2021 - liebertpub.com
Circular RNAs have been shown to regulate cancer tumorigenesis and drug resistance.
Recently, circCCND1 is reported to promote laryngeal squamous cell carcinoma; however …

Silencing circPVT1 enhances radiosensitivity in non-small cell lung cancer by sponging microRNA-1208

M Huang, T Li, Q Wang, C Li, H Zhou… - Cancer …, 2021 - content.iospress.com
BACKGROUND: Radiotherapy is one of main useful therapies in non-small cell lung cancer
(NSCLC). Nevertheless, the underlying mechanism between NSCLC cell radiosensitivity …

Elevated circASCC3 limits antitumor immunity by sponging miR-432–5p to upregulate C5a in non-small cell lung cancer

J Gao, LX Zhang, YQ Ao, C Jin, PF Zhang, H Wang… - Cancer Letters, 2022 - Elsevier
Although anti-programmed cell death 1 (PD1) treatment has become a first-line therapy for
advanced non-small cell lung cancer (NSCLC), most NSCLC patients are refractory to anti …