Oligofructose restores postprandial short‐chain fatty acid levels during high‐fat feeding

RK Meyer, AI Lane, SN Weninger, TM Martinez… - …, 2022 - Wiley Online Library
Objective Obesity is associated with consumption of a Western diet low in dietary fiber, while
prebiotics reduce body weight. Fiber induces short‐chain fatty acid (SCFA) production, and …

Oligosaccharide and short-chain fatty acid: a double-edged sword in obese mice by regulating food intake and fat synthesis

K Chen, M Hu, M Tang, C Gao, H Wang, S Man… - Food Research …, 2022 - Elsevier
Dietary fiber has been used to prevent obesity by regulating the intestinal flora and
promoting the production of short-chain fatty acids (SCFAs). However, it is insufficient to …

Different types of soluble fermentable dietary fibre decrease food intake, body weight gain and adiposity in young adult male rats

CL Adam, PA Williams, MJ Dalby, K Garden… - Nutrition & …, 2014 - Springer
Background Dietary fibre-induced satiety offers a physiological approach to body weight
regulation, yet there is lack of scientific evidence. This experiment quantified food intake …

[HTML][HTML] 2′-fucosyllactose alone or combined with resistant starch increases circulating short-chain fatty acids in lean men and men with prediabetes and obesity

EE Canfora, LMM Vliex, T Wang, A Nauta… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background Infusion of short-chain fatty acids (SCFA) to the distal colon beneficially affects
human substrate and energy metabolism. Here, we hypothesized that the combination of …

Supplementation of oligofructose, but not sucralose, decreases high‐fat diet induced body weight gain in mice independent of gustducin‐mediated gut hormone …

S Steensels, L Cools, B Avau… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope Enteroendocrine cells sense nutrients through taste receptors similar to those on the
tongue. Sweet and fatty acid taste receptors (FFAR) coupled to the gustatory G‐protein …

Oligofructose promotes satiety in rats fed a high‐fat diet: involvement of glucagon‐like peptide‐1

PD Cani, AM Neyrinck, N Maton… - Obesity …, 2005 - Wiley Online Library
Objective: To analyze the putative interest of oligofructose (OFS) in the modulation of food
intake after high‐fat diet in rats and to question the relevance of the expression and …

[HTML][HTML] Comparison of the effects of soluble corn fiber and fructooligosaccharides on metabolism, inflammation, and gut microbiome of high-fat diet-fed mice

M Van Hul, K Karnik… - American Journal …, 2020 - journals.physiology.org
Dietary fibers are essential components of a balanced diet and have beneficial effects on
metabolic functions. To gain insight into their impact on host physiology and gut microbiota …

The short-chain fatty acid uptake fluxes by mice on a guar gum supplemented diet associate with amelioration of major biomarkers of the metabolic syndrome

G den Besten, R Havinga, A Bleeker, S Rao… - PloS one, 2014 - journals.plos.org
Studies with dietary supplementation of various types of fibers have shown beneficial effects
on symptoms of the metabolic syndrome. Short-chain fatty acids (SCFAs), the main products …

Oligofructose improves small intestinal lipid-sensing mechanisms via alterations to the small intestinal microbiota

SN Weninger, C Herman, RK Meyer, ET Beauchemin… - Microbiome, 2023 - Springer
Background Upper small intestinal dietary lipids activate a gut-brain axis regulating energy
homeostasis. The prebiotic, oligofructose (OFS) improves body weight and adiposity during …

Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3

H Shimizu, Y Masujima, C Ushiroda, R Mizushima… - Scientific reports, 2019 - nature.com
Fermented foods represent a significant portion of human diets with several beneficial
effects. Foods produced by bacterial fermentation are enriched in short-chain fatty acids …