Abstract The human 16p11. 2 gene locus is a hot spot for copy number variations, which
predispose carriers to a range of neuropsychiatric phenotypes. Microduplications of 16p11 …

Neuropsychiatric disorders (NPDs) are frequently co-morbid with epilepsy, but the biological
basis of shared risk remains poorly understood. The 16p11. 2 duplication is a copy number …

Summary Chromosome 16p11. 2 duplications dramatically increase risk for schizophrenia,
but the mechanisms remain largely unknown. Here, we show that mice with an equivalent …

A deletion on human chromosome 16p11. 2 is associated with autism spectrum disorders.
We deleted the syntenic region on mouse chromosome 7F3. MRI and high-throughput …

Abstract Genetic 16p11. 2 and 22q11. 2 deletions and duplications in humans may alter
behavioral developmental trajectories increasing the risk of autism and schizophrenia …

Copy number variations (CNVs) of the human 16p11. 2 genetic locus are associated with a
range of neurodevelopmental disorders, including autism spectrum disorder, intellectual …

Microdeletion of the human 16p11. 2 gene locus has been linked to autism spectrum
disorder (ASD) and intellectual disability and confers risk for a number of other …

Background Microdeletion of the human 16p11. 2 gene locus confers risk for autism
spectrum disorders and intellectual disability. How 16p11. 2 deletion is linked to these …

Abstract 3q29 microdeletion, a rare recurrent copy number variant (CNV), greatly confers an
increased risk of psychiatric disorders, such as schizophrenia and autism spectrum disorder …

Autism spectrum disorders (ASDs) have garnered significant attention as an important
grouping of developmental brain disorders. Recent genomic studies have revealed that …