Background: Tranexamic acid (TXA) reduces bleeding and the need for transfusion after
total knee arthroplasty. Most literature has focused on intravenous (IV) administration of TXA …

Purpose This meta-analysis was designed to compare the effectiveness and safety of
intravenous (IV) versus topical administration of tranexamic acid (TXA) in patients …

Abundant literature confirms that intravenous (IV) and intra-articular (IA) administration of
tranexamic acid (TXA) reduces blood loss in total knee arthroplasty (TKA). Oral formulations …

Background Total knee arthroplasty (TKA) is associated with substantial blood loss in
postoperative period. Tranexamic acid (TXA) is potent antifibrinolytic agent, routinely …

Introduction Tranexamic acid (TXA) is becoming widely used in orthopedic surgery to reduce
blood loss and transfusion requirements, but consensus is lacking regarding the optimal …

Background To investigate the clinical effectiveness of intravenous (IV) and topical
tranexamic acid (TXA) in patients undergoing total knee arthroplasty (TKA) by comparing …

Background Tranexamic acid (TXA) is an antifibrinolytic drug used widely to prevent
bleeding in total knee arthroplasty (TKA). However, there is no consensus regarding the …

Background The mode of administration for tranexamic acid (TXA) to significantly reduce the
decrease in hemoglobin (Hb), number of transfusions, relevant costs, and side effects in …

The objective of this study is to compare the effectiveness of intravenous versus topical
application of tranexamic acid in patients undergoing knee arthroplasty. All patients who …

Background Use of tranexamic acid (TXA) is effective and safe in reducing the blood loss in
total knee arthroplasty (TKR) performed using a tourniquet, but, data in TKR performed …