AUTS2 regulation of synapses for proper synaptic inputs and social communication
K Hori, K Yamashiro, T Nagai, W Shan, SF Egusa… - IScience, 2020 - cell.com
Impairments in synapse development are thought to cause numerous psychiatric disorders.
Autism susceptibility candidate 2 (AUTS2) gene has been associated with various …
Autism susceptibility candidate 2 (AUTS2) gene has been associated with various …
AUTS2 governs cerebellar development, purkinje cell maturation, motor function and social communication
K Yamashiro, K Hori, ESK Lai, R Aoki, K Shimaoka… - IScience, 2020 - cell.com
Summary Autism susceptibility candidate 2 (AUTS2), a risk gene for autism spectrum
disorders (ASDs), is implicated in telencephalon development. Because AUTS2 is also …
disorders (ASDs), is implicated in telencephalon development. Because AUTS2 is also …
Heterozygous Disruption of Autism susceptibility candidate 2 Causes Impaired Emotional Control and Cognitive Memory
K Hori, T Nagai, W Shan, A Sakamoto, M Abe… - PLoS …, 2015 - journals.plos.org
Mutations in the Autism susceptibility candidate 2 gene (AUTS2) have been associated with
a broad range of psychiatric illnesses including autism spectrum disorders, intellectual …
a broad range of psychiatric illnesses including autism spectrum disorders, intellectual …
AUTS2 Gene: Keys to Understanding the Pathogenesis of Neurodevelopmental Disorders
K Hori, K Shimaoka, M Hoshino - Cells, 2021 - mdpi.com
Neurodevelopmental disorders (NDDs), including autism spectrum disorders (ASD) and
intellectual disability (ID), are a large group of neuropsychiatric illnesses that occur during …
intellectual disability (ID), are a large group of neuropsychiatric illnesses that occur during …
Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis
K Hori, T Nagai, W Shan, A Sakamoto, S Taya… - Cell reports, 2014 - cell.com
Mutations in the Autism susceptibility candidate 2 gene (AUTS2), whose protein is believed
to act in neuronal cell nuclei, have been associated with multiple psychiatric illnesses …
to act in neuronal cell nuclei, have been associated with multiple psychiatric illnesses …
Untangle the multi-facet functions of Auts2 as an entry point to understand neurodevelopmental disorders
W Pang, X Yi, L Li, L Liu, W Xiang, L Xiao - Frontiers in Psychiatry, 2021 - frontiersin.org
Neurodevelopmental disorders are psychiatric diseases that are usually first diagnosed in
infancy, childhood and adolescence. Autism spectrum disorder (ASD) is a …
infancy, childhood and adolescence. Autism spectrum disorder (ASD) is a …
The role of AUTS2 in neurodevelopment and human evolution
N Oksenberg, N Ahituv - Trends in Genetics, 2013 - cell.com
The autism susceptibility candidate 2 (AUTS2) gene is associated with multiple neurological
diseases, including autism, and has been implicated as an important gene in human …
diseases, including autism, and has been implicated as an important gene in human …
Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms
J Li, X Sun, Y You, Q Li, C Wei, L Zhao, M Sun… - Science …, 2022 - science.org
The involvement of genetic risk and the underlying developmental and neural circuit
mechanisms in autism-related social deficit are largely unclear. Here, we report that deletion …
mechanisms in autism-related social deficit are largely unclear. Here, we report that deletion …
Genome-wide distribution of Auts2 binding localizes with active neurodevelopmental genes
N Oksenberg, GDE Haliburton, WL Eckalbar… - Translational …, 2014 - nature.com
The autism susceptibility candidate 2 gene (AUTS2) has been associated with multiple
neurological diseases including autism spectrum disorders (ASDs). Previous studies …
neurological diseases including autism spectrum disorders (ASDs). Previous studies …
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses
Autism spectrum disorder (ASD) is a group of developmental disabilities characterized by
impairments in social interaction and communication and restricted and repetitive …
impairments in social interaction and communication and restricted and repetitive …