Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases

Z Chen, W Ding, X Yang, T Lu, Y Liu - Journal of ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …

[HTML][HTML] Novel isoquinoline alkaloid Litcubanine Aa potential anti-inflammatory candidate

H Xia, Y Liu, G Xia, Y Liu, S Lin, L Guo - Frontiers in Immunology, 2021 - frontiersin.org
Macrophages play a critical role in innate and adaptive immunity, and the regulation of
macrophage function in inflammatory disease treatment has been widely studied. Litsea …

Isoliquiritigenin prevents the progression of psoriasis-like symptoms by inhibiting NF-κB and proinflammatory cytokines

Y Wu, X Chen, X Ge, H Xia, Y Wang, S Su, W Li… - Journal of molecular …, 2016 - Springer
Isoliquiritigenin (ISL) is an important flavonoid component of licorice and has been reported
to possess anti-inflammatory and antioxidant properties, but its exact mechanism of action …

[HTML][HTML] Evidence for anti-inflammatory activity of isoliquiritigenin, 18β glycyrrhetinic acid, ursolic acid, and the traditional Chinese medicine plants Glycyrrhiza glabra …

JX Zhou, M Wink - Medicines, 2019 - mdpi.com
Background: We investigated the effect of root extracts from the traditional Chinese medicine
(TCM) plants Glycyrrhiza glabra L., Paeonia lactiflora Pall., and the leaf extract of Eriobotrya …

Impact of Icariin and its derivatives on inflammatory diseases and relevant signaling pathways

Z Luo, J Dong, J Wu - International immunopharmacology, 2022 - Elsevier
Herba Epimedii is a famous herb collected from China and Korea. It has been used for
impotency, osteoporosis, and amnestic treatment for thousands of years. Icariin, a typical …

A review: the pharmacology of isoliquiritigenin

F Peng, Q Du, C Peng, N Wang, H Tang… - Phytotherapy …, 2015 - Wiley Online Library
Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants
belonging to licorice, including Glycyrrhiza uralensis, Mongolian glycyrrhiza, Glycyrrhiza …

Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-κB in RAW 264.7 …

JY Kim, SJ Park, KJ Yun, YW Cho, HJ Park… - European journal of …, 2008 - Elsevier
In this study, the anti-inflammatory effects of flavonoids isolated from the roots of Glycyrrhiza
uralensis (Leguminosae), namely, isoliquiritin (the glycoside of isoliquirigenin) and …

Scropolioside B Inhibits IL‐1β and Cytokines Expression through NF‐κB and Inflammasome NLRP3 Pathways

T Zhu, L Zhang, S Ling, J Duan, F Qian… - Mediators of …, 2014 - Wiley Online Library
Chronic inflammation is associated with various chronic illnesses including immunity
disorders, cancer, neurodegeneration, and vascular diseases. Iridoids are compounds with …

Liquiritigenin, isoliquiritigenin rich extract of glycyrrhiza glabra roots attenuates inflammation in macrophages and collagen-induced arthritis in rats

V Babu, DS Kapkoti, M Binwal, RS Bhakuni… - …, 2023 - Springer
Liquiritigenin (LTG) and its bioprecursor isoliquiritigenin (ISL), the main bioactives from roots
of Glycyrrhiza genus are progressively documented as a potential pharmacological agent for …

The Protective Effects and Potential Mechanisms of Ligusticum chuanxiong: Focus on Anti‐Inflammatory, Antioxidant, and Antiapoptotic Activities

J Shi, R Li, S Yang, Y Phang, C Zheng… - Evidence‐Based …, 2020 - Wiley Online Library
Ligusticum chuanxiong (LC) is a Chinese materia medica which is widely used in clinical
settings to treat headaches, blood extravasation, and arthritis. Recent studies demonstrate …