[HTML][HTML] Epigenetic regulation by KDM5A mediates the effects of prenatal PM2. 5 exposure on hippocampal development and synaptic integrity through the Shh …
J Huang, C Song, Y Liu, T Zhang, T Wang, X Liu… - … and Environmental Safety, 2024 - Elsevier
Prenatal environmental exposure could be an essential health risk factor associated with
neurodevelopmental disorders in offspring. However, the exact mechanisms underlying the …
neurodevelopmental disorders in offspring. However, the exact mechanisms underlying the …
[HTML][HTML] Gestational exposure to PM2. 5 leads to cognitive dysfunction in mice offspring via promoting HMGB1-NLRP3 axis mediated hippocampal inflammation
T Zhang, L Sun, T Wang, C Liu, H Zhang… - Ecotoxicology and …, 2021 - Elsevier
PM 2.5 is recently identified as a kind of material possessing severe biohazard. It can enter
human body and exerts pathological effects on lung, eyes, and the central nervous system …
human body and exerts pathological effects on lung, eyes, and the central nervous system …
Exposure to PM2.5 causes genetic changes in fetal rat cerebral cortex and hippocampus
ABSTRACT PM2. 5 travels along the respiratory tract and enters systemic blood circulation.
Studies have shown that PM2. 5 increases the incidence of various diseases not only in …
Studies have shown that PM2. 5 increases the incidence of various diseases not only in …
Transgenerational transmission of neurodevelopmental disorders induced by maternal exposure to PM2. 5
Y Zhou, M Zhang, W Liu, Y Li, Y Qin, Y Xu - Chemosphere, 2020 - Elsevier
The pathological traits or diseases susceptibility caused by maternal exposure to
environmental adverse insults (infection, malnutrition, environmental toxicants) could be …
environmental adverse insults (infection, malnutrition, environmental toxicants) could be …
[HTML][HTML] Role of PKA/CREB/BDNF signaling in PM2. 5-induced neurodevelopmental damage to the hippocampal neurons of rats
J Liu, B Liu, P Yuan, L Cheng, H Sun, J Gui… - Ecotoxicology and …, 2021 - Elsevier
Exposure to fine particulate matter (PM2. 5) is implicated in neurodevelopmental disorders
including cognitive decline, attention-deficit/hyperactivity disorder, and autism spectrum …
including cognitive decline, attention-deficit/hyperactivity disorder, and autism spectrum …
[HTML][HTML] HMGB1-NLRP3-P2X7R pathway participates in PM2. 5-induced hippocampal neuron impairment by regulating microglia activation
C Liu, Y She, J Huang, Y Liu, W Li, C Zhang… - Ecotoxicology and …, 2022 - Elsevier
Neuroinflammation is a key mechanism underlying the cognitive impairment induced by PM
2.5, and activated microglia plays an important role in this process. However, the …
2.5, and activated microglia plays an important role in this process. However, the …
Hippocampal developmental vulnerability to methylmercury extends into prepubescence
M Obiorah, E McCandlish, B Buckley… - Frontiers in …, 2015 - frontiersin.org
The developing brain is sensitive to environmental toxicants such as methylmercury (MeHg),
to which humans are exposed via contaminated seafood. Prenatal exposure in children is …
to which humans are exposed via contaminated seafood. Prenatal exposure in children is …
Transcriptome sequencing analysis reveals a potential role of lncRNA NONMMUT058932. 2 and NONMMUT029203. 2 in abnormal myelin development of male …
Y Hou, W Yan, G Li, N Sang - Science of The Total Environment, 2023 - Elsevier
Numerous epidemiological studies have shown that PM 2.5 exposure in early life can
influence brain development and increase the risk of neurodevelopmental disorders in boys …
influence brain development and increase the risk of neurodevelopmental disorders in boys …
[HTML][HTML] The dysfunctionality of hippocampal synapses may be directly related to PM-induced impairments in spatial learning and memory in juvenile rats
J Gui, J Liu, Z Han, X Yang, R Ding, J Yang… - Ecotoxicology and …, 2023 - Elsevier
Epidemiological studies have demonstrated that exposure to air particulate matter (PM)
increases the incidence of cardiovascular and respiratory diseases and exerts a significant …
increases the incidence of cardiovascular and respiratory diseases and exerts a significant …
[HTML][HTML] In utero exposure to methylmercury impairs cognitive function in adult offspring: Insights from proteomic modulation
W Wang, L Zhang, C Deng, F Chen, Q Yu, Y Hu… - Ecotoxicology and …, 2022 - Elsevier
Methylmercury (MeHg) is a hazardous substance that has unique neurodevelopmental toxic
effects. However, its molecular alteration profile, sensitive response biomarkers, and …
effects. However, its molecular alteration profile, sensitive response biomarkers, and …