Background: Epigenetic disruptions have been implicated in neurodevelopmental disorders.
NSD2 is associated with developmental delay/intellectual disability; however, its role in …

The developing brain is particularly sensitive to exposures to environmental contaminants.
In contrast to the adult, the developing brain contains large numbers of dividing neuronal …

Methylmercury (MeHg) is a highly neurotoxic environmental chemical that can cause
developmental impairments. Human fetuses and neonates are particularly susceptible to …

Methylmercury (MeHg) is a potent environmental neurotoxin that shows toxicity to
developing central nervous system (CNS), causing brain damage in children even at low …

Lysine demethylase KDM7A removes histone modifications H3K9me1/2 and H3K27me1/2.
KDM7A plays critical roles in gene expression and contribute to biological processes …

The association between prenatal phthalate mixture exposure and the risk of autism
spectrum disorder (ASD) in children, as well as the potential mechanism and impact of …

Di-(2-ethylhexyl) phthalate (DEHP), as a prevalent xenoestrogen endocrine disrupter, is
omnipresent in the environment and commonly used in polyethylene plastic products …

Depression, anxiety and related mood disorders are major psychiatric illnesses worldwide,
and chronic stress appears to be one of the primary underlying causes. Therapeutics to treat …

The secreted glycoprotein Dickkopf-1 (Dkk1), an antagonist of the Wnt/β-catenin pathway,
has been implicated in many neurodegenerative diseases. However, it is unknown whether …

Mercury (Hg) is a toxic heavy-metal element, which can be enriched in fauna and flora and
transformed into methylmercury (MeHg). MeHg is a widely distributed environmental …