Ascorbic acid, thiamine, and steroids in septic shock: propensity matched analysis
F Sadaka, J Grady, N Organti… - Journal of intensive …, 2020 - journals.sagepub.com
Introduction: We aimed to study the use of ascorbic acid, thiamine, and steroids (ATS) in
patients with septic shock (SS). Methods: Data on 62 patients with SS were collected from …
patients with septic shock (SS). Methods: Data on 62 patients with SS were collected from …
Effect of ascorbic acid, corticosteroids, and thiamine on organ injury in septic shock: the ACTS randomized clinical trial
Importance The combination of ascorbic acid, corticosteroids, and thiamine has been
identified as a potential therapy for septic shock. Objective To determine whether the …
identified as a potential therapy for septic shock. Objective To determine whether the …
Ascorbic acid, corticosteroids and thiamine in sepsis (ACTS) protocol and statistical analysis plan: a prospective, multicentre, double-blind, randomised, placebo …
A Moskowitz, T Yankama, LW Andersen, DT Huang… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Septic shock is a common and highly morbid condition. To date, there is no
specific therapy proven to attenuate organ injury in septic shock. Recent studies have …
specific therapy proven to attenuate organ injury in septic shock. Recent studies have …
The Use of Hydrocortisone, Ascorbic Acid and Thiamine in Patients with Sepsis and Septic Shock–A Systematic Review
Background: Sepsis and septic shock are associated with enormous mortality and health
care burden. Since the study of Marik et al suggested mortality benefit, there has been great …
care burden. Since the study of Marik et al suggested mortality benefit, there has been great …
Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study
Purpose To evaluate the effects of early combination therapy with intravenous vitamin C and
thiamine on recovery from organ failure in patients with septic shock. Methods The ascorbic …
thiamine on recovery from organ failure in patients with septic shock. Methods The ascorbic …
Steroid, ascorbic acid, and thiamine in adults with sepsis and septic shock: a systematic review and component network meta-analysis
KM Fong, SY Au, GWY Ng - Scientific reports, 2021 - nature.com
To assess the effect from individual component in combinations of steroid, ascorbic acid,
and thiamine on outcomes in adults with sepsis and septic shock with component network …
and thiamine on outcomes in adults with sepsis and septic shock with component network …
Hydrocortisone, ascorbic acid, and thiamine (HAT) for sepsis and septic shock: a meta-analysis with sequential trial analysis
W Na, H Shen, Y Li, D Qu - Journal of Intensive Care, 2021 - Springer
Background Sepsis is a primary global health threat and costs a lot, requiring effective and
affordable treatments. We performed this meta-analysis to explore the treatment of …
affordable treatments. We performed this meta-analysis to explore the treatment of …
Efficacy of ascorbic acid, thiamine, and hydrocortisone combination therapy: meta-analysis of randomized controlled trials
T Kato, T Mizuno, M Nakanishi, JK Lee, S Yamada… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: Sepsis is a life-threatening biological condition that induces systemic
tissue and organ dysfunction and confers a high mortality risk. Although the use of …
tissue and organ dysfunction and confers a high mortality risk. Although the use of …
Use of hydrocortisone, ascorbic acid, and thiamine in adults with septic shock
Rationale: In December 2016, a single-center study describing significant improvements in
mortality among a small group of patients with severe sepsis and septic shock treated with …
mortality among a small group of patients with severe sepsis and septic shock treated with …
Outcomes of metabolic resuscitation using ascorbic acid, thiamine, and glucocorticoids in the early treatment of sepsis: the ORANGES trial
J Iglesias, AV Vassallo, VV Patel, JB Sullivan… - Chest, 2020 - Elsevier
Background Sepsis is a major public health burden resulting in 25% to 30% in-hospital
mortality and accounting for over 20 billion dollars of US hospital costs. Research Question …
mortality and accounting for over 20 billion dollars of US hospital costs. Research Question …
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