The pulmonary vasculature has been frequently overlooked in acute and chronic lung
diseases, such as acute respiratory distress syndrome (ARDS), pulmonary fibrosis (PF), and …

The European Respiratory Society (ERS) Research Seminar entitled “Pulmonary vascular
endothelium: orchestra conductor in respiratory diseases-highlights from basic research to …

The pulmonary endothelium is a dynamic, metabolically active layer of squamous
endothelial cells ideally placed to mediate key processes involved in lung homoeostasis …

Background: Pulmonary endothelium is an active organ possessing numerous
physiological, immunological, and metabolic functions. These functions may be altered early …

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality
worldwide and encompasses chronic bronchitis and emphysema. It has been shown that …

The pulmonary endothelium represents a heterogeneous cell monolayer covering the
luminal surface of the entire lung vasculature. As such, this cell layer lies at a critical …

Acute lung injury (ALI) and its most severe extreme the acute respiratory distress syndrome
(ARDS) refer to increased-permeability pulmonary edema caused by a variety of pulmonary …

In recent years there has been an increasing appreciation of the functional heterogeneity
that exists between extraalveolar and alveolar endothelial cells. One of the most striking …

Recently, angiogenesis and pulmonary vascular remodeling in COPD has been
investigated. It has been hypothesized that endothelial dysfunction might be an initiating …

Chronic lung diseases like COPD, severe progressive pulmonary hypertension (PH), and
interstitial lung diseases all have a lung vascular disease component. Cellular and …