The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …

Background context: Recent advances in neuroscience have opened the door for hope
toward prevention and cure of the devastating effects of spinal cord injury (SCI). Purpose: To …

Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …

Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

There is evidence from both clinical and experimental studies that the spinal cord suffers
both primary and secondary damage after acute spinal cord injury. The pathophysiology of …

Spinal cord injury (SCI) is a devastating and common neurologic disorder that has profound
influences on modern society from physical, psychosocial, and socioeconomic perspectives …

Neuroprotection refers to the attenuation of pathophysiological processes triggered by acute
injury to minimize secondary damage. The development of neuroprotective treatments …

OBJECTIVE: Experimental models and clinical observations of acute spinal cord injury (SCI)
support the concepts of primary and secondary injury, in which the initial mechanical insult is …

The pathophysiology of brain and spinal cord injury (SCI) is complex and involves multiple
injury mechanisms that are spatially and temporally specific. It is now appreciated that many …