Cellular specificity of NF-κB function in the nervous system

EC Dresselhaus, MK Meffert - Frontiers in immunology, 2019 - frontiersin.org
Nuclear Factor Kappa B (NF-κB) is a ubiquitously expressed transcription factor with key
functions in a wide array of biological systems. While the role of NF-κB in processes, such as …

NF-κB functions in the nervous system: from development to disease

S Mémet - Biochemical pharmacology, 2006 - Elsevier
The transcription factor nuclear factor-κB (NF-κB) is an ubiquitously expressed dimeric
molecule with post-translationally regulated activity. Its role in the immune system and host …

NF-κB in the nervous system

B Kaltschmidt, C Kaltschmidt - Cold Spring Harbor …, 2009 - cshperspectives.cshlp.org
The transcription factor NF-κB has diverse functions in the nervous system, depending on
the cellular context. NF-κB is constitutively activated in glutamatergic neurons. Knockout of …

Minimal NF-κB activity in neurons

SJ Listwak, P Rathore, M Herkenham - Neuroscience, 2013 - Elsevier
Nuclear factor-kappa B (NF-κB) is a ubiquitous transcription factor that regulates immune
and cell-survival signaling pathways. NF-κB has been reported to be present in neurons …

NF-kappaB signaling pathways in neurological inflammation: a mini review

RH Shih, CY Wang, CM Yang - Frontiers in molecular neuroscience, 2015 - frontiersin.org
The NF-κB (nuclear factor κ-light-chain-enhancer of activated B cells) transcription factor
family is a pleiotropic regulator of many cellular signaling pathways, providing a mechanism …

Distinct roles of diverse nuclear factor-κB complexes in neuropathological mechanisms

M Pizzi, PF Spano - European journal of pharmacology, 2006 - Elsevier
The nuclear transcription factors κB (NF-κB) function as key regulators of physiological
processes in the central nervous system. Aberrant regulation of NF-κB can underlie …

Roles for NF-κB in nerve cell survival, plasticity, and disease

MP Mattson, MK Meffert - Cell Death & Differentiation, 2006 - nature.com
Here we review evidence of roles for NF-κB in the regulation of developmental and synaptic
plasticity, and cell survival in physiological and pathological settings. Signaling pathways …

[HTML][HTML] Signaling via NF-κB in the nervous system

B Kaltschmidt, D Widera, C Kaltschmidt - Biochimica et Biophysica Acta …, 2005 - Elsevier
Nuclear factor kappa B (NF-κB) is an inducible transcription factor present in neurons and
glia. Recent genetic models identified a role for NF-κB in neuroprotection against various …

Nuclear factor-κB/Rel proteins: a point of convergence of signalling pathways relevant in neuronal function and dysfunction

M Grilli, M Memo - Biochemical pharmacology, 1999 - Elsevier
Nuclear factor-κB (NF-κB)/Rel designates a family of transcription factors participating in the
activation of a wide range of genes crucially involved in immune and inflammatory function …

Constitutive nuclear factor-κB activity is required for central neuron survival

AL Bhakar, LL Tannis, C Zeindler… - Journal of …, 2002 - Soc Neuroscience
The function of nuclear factor (NF)-κB within the developing and mature CNS is
controversial. We have generated transgenic mice to reveal NF-κB transcriptional activity in …