[HTML][HTML] Role of short chain fatty acids in gut health and possible therapeutic approaches in inflammatory bowel diseases

MAF Caetano, P Castelucci - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBDs) are characterized by inflammation in the
gastrointestinal tract and include Ulcerative Colitis and Crohn's Disease. These diseases …

Short‐chain fatty acids affect the development of inflammatory bowel disease through intestinal barrier, immunology, and microbiota: A promising therapy?

K Peng, S Xia, S Xiao, Q Yu - Journal of gastroenterology and …, 2022 - Wiley Online Library
Intestinal metabolites are attracting increasing interest, especially more and more studies
have found they are closely related to diseases. Microbial fermentation of indigestible …

Regulatory role of short-chain fatty acids in inflammatory bowel disease

Z Zhang, H Zhang, T Chen, L Shi, D Wang… - Cell Communication and …, 2022 - Springer
Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory disorders of
the gastrointestinal tract. Accumulating evidence shows that the development of IBD is …

Effects of short chain fatty acids on metabolic and inflammatory processes in human health

W Campos-Perez, E Martinez-Lopez - … (BBA)-Molecular and Cell Biology of …, 2021 - Elsevier
Butyrate, propionate, and acetate are short-chain fatty acids (SCFAs) mainly produced by
bacterial metabolism in the human gut after dietary fiber intake. SCFAs are considered …

Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?

S Deleu, K Machiels, J Raes, K Verbeke, S Vermeire - EBioMedicine, 2021 - thelancet.com
The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …

Pathobiology and potential therapeutic value of intestinal short-chain fatty acids in gut inflammation and obesity

J Soldavini, JD Kaunitz - Digestive diseases and sciences, 2013 - Springer
Background The lumen of the gastrointestinal tract contains many substances produced
from the breakdown of foodstuffs, from salivary, esophageal, intestinal, hepatic, and …

Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases

M Sun, W Wu, Z Liu, Y Cong - Journal of gastroenterology, 2017 - Springer
Gut microbiota has been well recognized in regulation of intestinal homeostasis and
pathogenesis of inflammatory bowel diseases. However, the mechanisms involved are still …

[HTML][HTML] Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation

M Akhtar, Y Chen, Z Ma, X Zhang, D Shi, JA Khan… - Animal nutrition, 2022 - Elsevier
Gut inflammation is a challenging concern in humans and animals, which disturbs normal
growth and leads to severe bowel diseases. Short chain fatty acids (SCFA) are the gut …

Roles of short-chain fatty acids in inflammatory bowel disease

Y Shin, S Han, J Kwon, S Ju, TG Choi, I Kang, SS Kim - Nutrients, 2023 - mdpi.com
The gut microbiome is a diverse bacterial community in the human gastrointestinal tract that
plays important roles in a variety of biological processes. Short-chain fatty acids (SCFA) are …

Short chain fatty acids as potential therapeutic agents in human gastrointestinal and inflammatory disorders

PA Gill, MC Van Zelm, JG Muir… - Alimentary …, 2018 - Wiley Online Library
Background Butyrate, propionate and acetate are short chain fatty acids (SCFA), important
for maintaining a healthy colon and are considered as protective in colorectal …