An overview of vaccine adjuvants: current evidence and future perspectives

A Facciolà, G Visalli, A Laganà, A Di Pietro - Vaccines, 2022 - mdpi.com
Vaccinations are one of the most important preventive tools against infectious diseases.
Over time, many different types of vaccines have been developed concerning the antigen …

[HTML][HTML] The continued advance of vaccine adjuvants–'we can work it out'

DT O'Hagan, RN Lodaya, G Lofano - Seminars in immunology, 2020 - Elsevier
In the last decade there have been some significant advances in vaccine adjuvants,
particularly in relation to their inclusion in licensed products. This was proceeded by several …

Emerging concepts in the science of vaccine adjuvants

B Pulendran, P S. Arunachalam… - Nature Reviews Drug …, 2021 - nature.com
Adjuvants are vaccine components that enhance the magnitude, breadth and durability of
the immune response. Following its introduction in the 1920s, alum remained the only …

Strategies for vaccination: conventional vaccine approaches versus new-generation strategies in combination with adjuvants

A Bouazzaoui, AAH Abdellatif, FA Al-Allaf, NM Bogari… - Pharmaceutics, 2021 - mdpi.com
The current COVID-19 pandemic, caused by severe acute respiratory syndrome-coronavirus
2 (SARS-CoV-2), has raised significant economic, social, and psychological concerns. The …

SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways

D Mekonnen, HM Mengist, T Jin - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Vaccines are the agreed upon weapon against the COVID-19 pandemic. This
review discusses about COVID-19 subunit vaccines adjuvants and their signaling pathways …

[HTML][HTML] Advancements in vaccine adjuvants: The journey from alum to nano formulations

SS Moni, SI Abdelwahab, A Jabeen, ME Elmobark… - Vaccines, 2023 - mdpi.com
Vaccination is a groundbreaking approach in preventing and controlling infectious diseases.
However, the effectiveness of vaccines can be greatly enhanced by the inclusion of …

Adjuvants for coronavirus vaccines

Z Liang, H Zhu, X Wang, B Jing, Z Li, X Xia… - Frontiers in …, 2020 - frontiersin.org
Vaccine development utilizing various platforms is one of the strategies that has been
proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are …

Vaccine adjuvants: Why and how

D Christensen - Human vaccines & immunotherapeutics, 2016 - Taylor & Francis
Novel vaccine strategies include the so-called subunit vaccines, which encompass only the
part of the pathogen to which immune recognition results in protection. The high purity of …

Current adjuvants and new perspectives in vaccine formulation

E Montomoli, S Piccirella, B Khadang… - Expert review of …, 2011 - Taylor & Francis
Given the important role of adjuvants in prophylactic vaccines, identification and
development of new adjuvants with enhanced efficacy and safety is necessary. The use of …

[HTML][HTML] Selection of adjuvants for enhanced vaccine potency

W Wang, M Singh - World Journal of Vaccines, 2011 - scirp.org
The advent of mass vaccination has saved millions of human lives and revolutionized the
quality of life. Vaccination is currently one of the most cost effective ways of managing …