Harnessing anti‐tumor and tumor‐tropism functions of macrophages via nanotechnology for tumor immunotherapy
Y Zheng, Y Han, Q Sun, Z Li - Exploration, 2022 - Wiley Online Library
Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …
macrophages holds great promise in tumor immunotherapy. As a class of professional …
Nanomedicine-based cancer immunotherapies developed by reprogramming tumor-associated macrophages
Tumor microenvironment is a complex ecosystem composed of tumor extracellular matrix,
fibroblasts, blood vessels, and immune cells, promoting tumor development by secreting …
fibroblasts, blood vessels, and immune cells, promoting tumor development by secreting …
Engineering macrophages for cancer immunotherapy and drug delivery
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Nanomaterials targeting tumor associated macrophages for cancer immunotherapy
Tumor-associated macrophages (TAMs) play an important role in regulating tumor growth,
invasion and metastasis, and constitute approximately 50% of tumor mass. TAMs can exist …
invasion and metastasis, and constitute approximately 50% of tumor mass. TAMs can exist …
Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
Cancer immunotherapy has emerged as a novel cancer treatment, although recent
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
immunotherapy trials have produced suboptimal outcomes, with durable responses seen …
Tailoring nanomaterials for targeting tumor‐associated macrophages
Advances in the field of nanotechnology together with an increase understanding of tumor
immunology have paved the way for the development of more personalized cancer immuno …
immunology have paved the way for the development of more personalized cancer immuno …
Tackling TAMs for cancer immunotherapy: it's nano time
The tumor microenvironment (TME) is a highly complex environment that surrounds tumors.
Interactions between cancer cells/non-cancerous cells and cells/non-cell components in the …
Interactions between cancer cells/non-cancerous cells and cells/non-cell components in the …
Macrophage‐mediated tumor cell phagocytosis: opportunity for nanomedicine intervention
Macrophages are one of the most abundant non‐malignant cells in the tumor
microenvironment, playing critical roles in mediating tumor immunity. As important innate …
microenvironment, playing critical roles in mediating tumor immunity. As important innate …
[HTML][HTML] Tumor microenvironment remodeling and tumor therapy based on M2-like tumor associated macrophage-targeting nano-complexes
S Han, W Wang, S Wang, T Yang, G Zhang, D Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Among the many immunosuppressive cells in the tumor microenvironment,
tumor-associated-macrophages (TAMs) are well known to contribute to tumor development …
tumor-associated-macrophages (TAMs) are well known to contribute to tumor development …
Functionalized nanoparticles targeting tumor-associated macrophages as cancer therapy
Y He, RF de Araújo Júnior, LJ Cruz, C Eich - Pharmaceutics, 2021 - mdpi.com
The tumor microenvironment (TME) plays a central role in regulating antitumor immune
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …
responses. As an important part of the TME, alternatively activated type 2 (M2) macrophages …