FAM13A polymorphisms are associated with a specific susceptibility to clinical progression of oral cancer in alcohol drinkers

MJ Hsieh, YS Lo, YJ Tsai, HY Ho, CC Lin, YC Chuang… - BMC cancer, 2023 - Springer
Background Single nucleotide polymorphism (SNP) is a genetic variation that occurs when a
single nucleotide base in the DNA sequence varies between individuals and is present in at …

FAM13A locus in COPD is independently associated with lung cancer – evidence of a molecular genetic link between COPD and lung cancer

RP Young, RJ Hopkins, BA Hay… - The application of …, 2010 - Taylor & Francis
Recent genome-wide association studies have reported a FAM13A variant on chromosome
4q22. 1 is associated with lung function and COPD. We examined this variant in a case …

Functional Variant in 3′UTR of FAM13A Is Potentially Associated with Susceptibility and Survival of Lung Squamous Carcinoma

Y Yu, L Mao, X Lu, W Yuan, Y Chen, L Jiang… - DNA and cell …, 2019 - liebertpub.com
FAM13A is associated with aging lung disease (primarily chronic obstructive pulmonary
disorder and pulmonary fibrosis) and shows stable expression throughout lung …

Multiple single nucleotide polymorphism analysis and association of specific genotypes in FHIT, SAMD4A, and ANKRD17 in Indian patients with oral cancer

W D'Souza, S Pradhan, D Saranath - Head & Neck, 2017 - Wiley Online Library
Background Oral cancer has a high incidence primarily because of tobacco chewing habits.
However, a small proportion of habitués develop oral cancer, implying a role for genomic …

Host genetic susceptibility to oral cancer: evidence from meta‐analyses and pooled analyses

G Liao, Y Wang, YQ Zhou, TW Li, DQ Zeng… - Oral …, 2014 - Wiley Online Library
Background A large number of meta‐analyses and pooled analyses have been published
on the topic of the genetic variants for oral cancer, and many positive results have been …

FAM3 family as prognostic factors for head and neck squamous cell carcinoma

C Liao, Q Wang, J An, H Wang, L Xiao… - … Chemistry & High …, 2023 - ingentaconnect.com
Background: Although head and neck squamous cell carcinoma (HNSCC) is a common
malignancy, the molecular biology landscape underlying its occurrence and development …

Variants in FAT1 and COL9A1 genes in male population with or without substance use to assess the risk factors for oral malignancy

CM Chung, CC Hung, CH Lee, CP Lee, KW Lee… - PLoS …, 2019 - journals.plos.org
A number of genetic variants were suggested to be associated with oral malignancy, few
variants can be replicated. The aim of this study was to identify significant variants that …

Association of FAM13A polymorphisms with COPD and COPD-related phenotypes in Han Chinese

B Wang, B Liang, J Yang, J Xiao, C Ma, S Xu, J Lei… - Clinical …, 2013 - Elsevier
Objectives Genome-wide association studies (GWAS) and integrative genomics approaches
have demonstrated significant associations between chronic obstructive pulmonary disease …

High expression of FAM13A was associated with increasing the liver cirrhosis risk

Y Zhang, S Wang, C Wang, J Xiao… - Molecular Genetics & …, 2019 - Wiley Online Library
Aim Liver cirrhosis is a consequence of chronic liver disease, and it may be caused by
multiple influences of both genetic and environmental factors. Family with sequence …

Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck

H Liu, G Li, EM Sturgis, S Shete… - … journal of cancer, 2022 - Wiley Online Library
Polycyclic aromatic hydrocarbons (PAH) and tobacco‐specific nitrosamines (TSNA)
metabolism‐related genes play an important role in the development of cancers. We …