Prevention of aspirin-mediated secondary toxicity by combined treatment of carotenoids in macrophages

K Vijay, R Ambedkar, PRR Sowmya, S Ramaiah… - 3 Biotech, 2023 - Springer
Upon understanding the boosting role of carotenoids on the endogenous anti-inflammatory
system, it is vital to explore their role in reducing the use of high doses of non-steroidal anti …

[PDF][PDF] Evaluation of anti-inflammatory and anti-proliferative effect of hydroxy-, keto-, and epoxy-carotenoids in RAW 264.7 and HL-60 cells

K Vijay, PR Sowmya, BP Arathi… - J Food Chem …, 2016 - Citeseer
Aim of the study was to investigate efficiency of hydroxy (lutein, LUT), Keto-(astaxanthin,
AST) and epoxy-(fucoxanthin, FUCO) carotenoids on molecular/biochemical events in …

[HTML][HTML] Astaxanthin targets IL-6 and alleviates the LPS-induced adverse inflammatory response of macrophages

Y Wu, MA Bashir, C Shao, H Wang, J Zhu, Q Huang - Food & Function, 2024 - pubs.rsc.org
Numerous natural compounds are recognized for their anti-inflammatory properties
attributed to antioxidant effects and the modulation of key inflammatory factors. Among them …

[HTML][HTML] Multivariate analysis reveals that unsubstituted β-ring and c8-keto structures are important factors for anti-inflammatory activity of carotenoids

Y Manabe, N Tomonaga, T Maoka, T Sugawara - Nutrients, 2021 - mdpi.com
Carotenoids are natural lipophilic pigments with substantial health benefits. Numerous
studies have demonstrated the anti-inflammatory activities of carotenoids, especially toward …

[HTML][HTML] Astaxanthin prevents against lipopolysaccharide-induced acute lung injury and sepsis via inhibiting activation of MAPK/NF-κB

X Cai, Y Chen, X Xie, D Yao, C Ding… - American journal of …, 2019 - ncbi.nlm.nih.gov
Background: Endotoxin-induced acute inflammatory diseases such as sepsis, mediated by
excessive production of various pro-inflammatory cytokines remain the leading cause of …

Regulation of virus-induced inflammatory response by β-carotene in RAW264. 7 cells

HW Lin, TJ Chang, DJ Yang, YC Chen, M Wang… - Food chemistry, 2012 - Elsevier
Carotenoids are effective antioxidants, which can quench singlet oxygen, suppress lipid
peroxidation, and prevent oxidative damage. Both Pseudorabies virus (PRV) and human …

Anti-inflammatory effect of fucoxanthinol as bioavailable marine carotenoid on LPS-stimulated RAW264. 7 macrophages through iNOS suppression and nitrogen …

J Taira, M Uehara - World Journal of Pharmaceutical Sciences, 2015 - wjpsonline.com
In this study, the anti-inflammatory effect of marine carotenoid fucoxanthinol (FXOH), a
deacetylated metabolite of fucoxanthin (FX) was assessed with nitric oxide (NO) reducing …

Squalene-based multidrug nanoparticles for improved mitigation of uncontrolled inflammation in rodents

F Dormont, R Brusini, C Cailleau, F Reynaud… - Science …, 2020 - science.org
Uncontrolled inflammatory processes are at the root of numerous pathologies. Most recently,
studies on confirmed COVID-19 cases have suggested that mortality might be due to virally …

β‐Carotene attenuates lipopolysaccharide‐induced inflammation via inhibition of the NF‐κB, JAK2/STAT3 and JNK/p38 MAPK signaling pathways in macrophages

R Li, P Hong, X Zheng - Animal Science Journal, 2019 - Wiley Online Library
Abstract β‐carotene is one of the most abundant carotenoids, has potential anti‐
inflammatory effect, it has been reported that β‐carotene could suppress LPS‐induced …

Protection against UVA damage and effects on neutrophil-derived reactive oxygen species by β-carotene

M Bohne, H Struy, A Gerber, H Gollnick - Inflammation Research, 1997 - Springer
Objective: Phagocyte-derived reactive oxygen species (ROS) are involved in microbicidal
activities as well as in tissue damage at sites of inflammation. Carotenoids play an important …