Pediatric ischemic stroke, though relatively rare, remains an important medical problem
since 20− 40% of patients have recurrent strokes and 50− 85% of them suffer from long-term …

The 4G/5G polymorphism in the plasminogen activator inhibitor-1 (PAI-1) gene, has been
associated with arterial disease. In this study, we investigated the association of IS in young …

Objectives: To investigate the relationship between an insertion/deletion (4G/5G)
polymorphism of the plasminogen activator inhibitor (PAI)‐1 gene and childhood patients …

Background Prolonged euglobulin clot lysis time (ECLT) and increased level of
plasminogen activator inhibitor-1 (PAI-1) were reported to be risk factors of arterial ischemic …

Background–Plasminogen activator inhibitor type 1 (PAI‐1) is the major inhibitor of
fibrinolysis. It was reported that PAI‐1 gene polymorphisms affected PAI‐1 level and might …

The role of genetic risk factors for ischemic stroke seems to be in particular significance in
pediatric patients. Numerous polymorphic variants of genes encoding proteins, that is …

The plasminogen activator inhibitor-1 (PAI-1) is a candidate gene for stroke based on PAI-
1's crucial role in fibrinolytic system. However, association studies have yielded conflicting …

Methods: A case-control genetic association study on PAI-1 polymorphism was conducted. It
contains 179 patients with ischemic stroke and 229 healthy controls. We also conducted a …

Background and Purpose: Decreased fibrinolytic capacity due to increased plasminogen
activator inhibitor-1 (PAI-1) activity and decreased tissue-type plasminogen activator (t-PA) …

The plasminogen activator inhibitor-1 (PAI-1) gene has been found to be associated with the
pathogenesis and progression of vascular diseases including stroke. A 4G/5G, PAI-1 gene …