Astrocytes are implicated in synapse formation and elimination, which are associated with
developmental refinements of neuronal circuits. Astrocyte dysfunctions are also linked to …

Astrocyte-derived factors can control synapse formation and functions, making astrocytes an
attractive target for regulating neuronal circuits and associated behaviors. Abnormal …

Ephrin (Eph) signaling via Eph receptors affects neuronal structure and function. We report
here that exogenous ephrinAs (EphAs) induce outgrowth of filopodial processes from …

Neurogenesis in the adult hippocampus involves activation of quiescent neural stem cells
(NSCs) to yield transiently amplifying NSCs, progenitors, and, ultimately, neurons that affect …

Background Synaptogenesis is a fundamental step in neuronal development. For spiny
glutamatergic synapses in hippocampus and cortex, synaptogenesis involves adhesion of …

Neuron–glia communication is essential for regulating the properties of synaptic
connections in the brain. Astrocytes, in particular, play a critical and complex role in synapse …

Glial cells are known to actively participate in neuronal development by shaping neuronal
connections through axon pruning and by controlling dendritic spine morphology. These …

The transmembrane ephrinB ligands and their Eph receptor tyrosine kinases are known to
regulate excitatory synaptic functions in the hippocampus. In the CA3–CA1 synapse …

Neurogenesis occurs throughout the life in the mammalian brain. The hippocampal dentate
gyrus (DG) is one of the major regions of the adult neurogenesis, where neural …

During development, Eph receptors mediate the repulsive axon guidance function of
ephrins, a family of membrane attached ligands with their own receptor-like signaling …