Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Abstract Purpose of Review Both conventional and novel approaches to early detection of
ovarian cancer are reviewed in the context of new developments in our understanding of …

Despite advances in therapy, ovarian cancer remains the most deadly of the gynecological
cancers. Less than 30% of women with advanced stage disease survive long‐term. When …

The history of biomarkers and ultrasonography dates back over more than 50 years. The
present status of biomarkers used in the context of ovarian cancer is addressed. Attention is …

The improved detection of ovarian cancer at the earliest stages of development would confer
a significant benefit in the therapeutic efficacy and overall survival associated with this …

Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer
symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well …

Each year in the United States over 15,000 women die of epithelial ovarian cancer (EOC)
and 22,000 are diagnosed with the disease. The incidence of ovarian cancer has remained …

The rationale for early detection of ovarian cancer is compelling. Ovarian cancer confined to
the ovaries (stage I) can be cured in up to 90% of patients, and disease confined to the …

This paper reviews current screening techniques as well as novel biomarkers and their
potential role in early detection of ovarian cancer. Ovarian cancer is one of the most …

Abstract The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
recently reported a reduction in the average overall mortality among ovarian cancer patients …