Radiation therapy (RT) is a curative treatment for many malignancies and provides effective
palliation in patients with tumor‐related symptoms. However, the biophysical effects of RT …

Objectives: Review the pathophysiology and common side effects of radiation therapy.
Outline strategies for the treatment of radiotherapy side effects. Describe the importance of …

Radiotherapy is used in> 50% of patients with cancer, both for curative and palliative
purposes. Radiotherapy uses ionizing radiation to target and kill tumour tissue, but normal …

Purpose of review Ionizing radiation is a highly effective treatment for a wide range of
malignancies, yet the cardiovascular (CV) toxicity that can result from chest radiotherapy …

Any tumor could be controlled by radiation therapy if sufficient dose were delivered to all
tumor cells. Although technological advances in physical treatment delivery have been …

To summarize current knowledge regarding mechanisms of radiation-induced normal tissue
injury and medical countermeasures available to reduce its severity. Advances in radiation …

As described in the previous article in this issue by Trotti et al, there have been major
changes in the philosophy and scope of the new National Cancer Institute comprehensive …

The target volume in curative radiotherapy must unavoidably include a substantial amount of
normal tissue, despite optimum conformation of the treatment fields to the tumour and …

Combined chemoradiotherapy is increasingly becoming a standard of care for the
nonoperative management of a variety of solid malignancies. A string of randomized …

Abstract The Canadian Cancer Society estimated that 220,400 new cases of cancer would
be diagnosed in 2019. Of the affected patients, more than 60% will survive for 5 years or …