Platforms for production of protein-based vaccines: from classical to next-generation strategies
R Cid, J Bolívar - Biomolecules, 2021 - mdpi.com
To date, vaccination has become one of the most effective strategies to control and reduce
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …
infectious diseases, preventing millions of deaths worldwide. The earliest vaccines were …
Non-conventional expression systems for the production of vaccine proteins and immunotherapeutic molecules
I Legastelois, S Buffin, I Peubez, C Mignon… - Human vaccines & …, 2017 - Taylor & Francis
The increasing demand for recombinant vaccine antigens or immunotherapeutic molecules
calls into question the universality of current protein expression systems. Vaccine production …
calls into question the universality of current protein expression systems. Vaccine production …
Production of recombinant subunit vaccines: protein immunogens, live delivery systems and nucleic acid vaccines
S Liljeqvist, S Ståhl - Journal of biotechnology, 1999 - Elsevier
The first scientific attempts to control an infectious disease can be attributed to Edward
Jenner, who, in 1796 inoculated an 8-year-old boy with cowpox (vaccinia), giving the boy …
Jenner, who, in 1796 inoculated an 8-year-old boy with cowpox (vaccinia), giving the boy …
Trained immunity-based vaccines: a new paradigm for the development of broad-spectrum anti-infectious formulations
S Sánchez-Ramón, L Conejero, MG Netea… - Frontiers in …, 2018 - frontiersin.org
Challenge with specific microbial stimuli induces long lasting epigenetic changes in innate
immune cells that result in their enhanced response to a second challenge by the same or …
immune cells that result in their enhanced response to a second challenge by the same or …
Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities
Vaccination is a key component of public health policy with demonstrated cost-effective
benefits in protecting both human and animal populations. Vaccines can be manufactured …
benefits in protecting both human and animal populations. Vaccines can be manufactured …
Recombinant vaccines in 2022: a perspective from the cell factory
MT de Pinho Favaro, J Atienza-Garriga… - Microbial cell …, 2022 - Springer
The last big outbreaks of Ebola fever in Africa, the thousands of avian influenza outbreaks
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …
across Europe, Asia, North America and Africa, the emergence of monkeypox virus in …
Novel vaccine technologies for the 21st century
JR Mascola, AS Fauci - Nature Reviews Immunology, 2020 - nature.com
Novel approaches to vaccine development include structure-based immunogen design,
gene-based vaccine platforms and formulation of recombinant antigens with potent …
gene-based vaccine platforms and formulation of recombinant antigens with potent …
Designing vaccines for the twenty-first century society
O Finco, R Rappuoli - Frontiers in immunology, 2014 - frontiersin.org
The history of vaccination clearly demonstrates that vaccines have been highly successful in
preventing infectious diseases, reducing significantly the incidence of childhood diseases …
preventing infectious diseases, reducing significantly the incidence of childhood diseases …
Recombinant protein vaccines produced in insect cells
MMJ Cox - Vaccine, 2012 - Elsevier
The baculovirus-insect cell expression system is a well known tool for the production of
complex proteins. The technology is also used for commercial manufacture of various …
complex proteins. The technology is also used for commercial manufacture of various …
Emerging technologies for low‐cost, rapid vaccine manufacture
To stop the spread of future epidemics and meet infant vaccination demands in low‐and
middle‐income countries, flexible, rapid and low‐cost vaccine development and …
middle‐income countries, flexible, rapid and low‐cost vaccine development and …