Stroke in children and young adults is a morbid disease responsible for enormous indirect
societal costs and a high burden of years with disability per affected patient. Recent …

Background Several randomized trials have shown the efficacy of thrombectomy for large
intracranial vessel occlusions in adults. However, the safety and efficacy of thrombectomy in …

Object Endovascular therapy has become a widely used method for achieving arterial
recanalization in patients who are ineligible for intravenous thrombolysis or those in whom it …

Importance The incidence and natural history of large vessel occlusion (LVO) stroke in
children is largely unknown. These knowledge gaps limit the uptake of reperfusion therapies …

Background Like adults, most children have lifelong morbidity after stroke. Revascularization
therapies such as intravenous tissue plasminogen activator and mechanical thrombectomy …

Objective Safety and efficacy data for endovascular thrombectomy for acute ischemic stroke
secondary to large-vessel occlusion in children are lacking compared with those for adults …

Importance Randomized clinical trials have shown the efficacy of thrombectomy of large
intracranial vessel occlusions in adults; however, any association of therapy with clinical …

Object: This study aims to evaluate the use of endovascular therapy to treat very young (≤
35 years) patients with acute ischemic stroke from large vessel occlusion. Methods We …

No controlled pharmacological studies are available in the field of pediatric stroke, except for
sickle cell disease. Therefore, while pharmacological and mechanical recanalization …

The use of mechanical thrombectomy for the treatment of acute childhood arterial ischemic
stroke with large vessel occlusion is increasing, with mounting evidence for its feasibility and …