The synaptic balance between excitation and inhibition (E/I balance) is a fundamental
principle of cortical circuits, and disruptions in E/I balance are commonly linked to cognitive …

In this chapter, we review a series of computational modeling studies using biophysically
based neural circuit models to study how disruptions of cortical excitation–inhibition (E/I) …

Decision-making biases can be features of normal behaviour, or deficits underlying
neuropsychiatric symptoms. We used behavioural psychophysics, spiking-circuit modelling …

A fundamental property of both local cortical and long-range neural computations involves a
balanced communication between two principal neuronal populations—excitatory and …

Most experimental studies of decision-making have specifically examined situations in
which a single correct answer exists (externally guided decision-making). Along with such …

Excitation–inhibition balance (E/I balance) is a fundamental property of cortical
microcircuitry. Disruption of E/I balance in prefrontal cortex is hypothesized to underlie …

Poor context integration, the process of incorporating both previous and current information
in decision making, is a cognitive symptom of schizophrenia. The maintenance of the …

Despite advances in techniques for exploring reciprocity in brain-behavior relations, few
studies focus on building neurocognitive models that describe both human EEG and …

Advantageous effects of cognitive control are well-known, but cognitive control may also
have adverse effects, for example when it suppresses the implicit processing of stimulus …

Recent physiological studies have shown that neurons in various regions of the central
nervous systems continuously receive noisy excitatory and inhibitory synaptic inputs in a …