The transplantation ecosystem: a new concept to improve access and outcomes for older allogeneic hematopoietic cell transplantation patients

SA Wall, R Olin, V Bhatt, S Chhabra, P Munshi… - … and Cellular Therapy, 2023 - Elsevier
Allogeneic hematopoietic cell transplantation (HCT) is increasingly offered to older adults
with hematologic malignancies, even though nonrelapse mortality remains a major concern …

[HTML][HTML] From biology to clinical practice: aging and hematopoietic cell transplantation

AS Artz - Biology of blood and marrow transplantation, 2012 - Elsevier
Poor long-term outcomes for many hematologic conditions that are standard indications in
younger adults have naturally pushed the potentially curative, albeit toxic, procedure of …

Hematopoietic cell transplantation in older adults: deciding or decision-making?

AS Artz, S Chow - Bone Marrow Transplantation, 2016 - nature.com
Historically, the high toxicities of allogeneic hematopoietic cell transplantation (HCT)
precluded this therapy in older adults. However, with more tolerable regimens, better donor …

Hematopoietic stem cell transplantation in older persons: respecting the heterogeneity of age

LC Michaelis, M Hamadani, PN Hari - Expert review of hematology, 2014 - Taylor & Francis
Demographic trends establish that older adults are the fastest growing segment of
population, with over 19% of the population expected to be aged> 65 years by 2030. As the …

Age barriers in allogeneic hematopoietic cell transplantation: Raising the silver curtain

PN Munshi, SR McCurdy - American Journal of Hematology, 2024 - Wiley Online Library
Allogeneic hematopoietic cell transplantation (HCT) is no longer exclusively for the young.
With an aging population, development of non‐intensive remission‐inducing strategies for …

Up-to-date tools for risk assessment before allogeneic hematopoietic cell transplantation

M Elsawy, ML Sorror - Bone marrow transplantation, 2016 - nature.com
Cure of malignant and non-malignant hematological diseases is potentially possible after
allogeneic hematopoietic stem cell transplantation (HCT). Accurate evaluation of the risk …

Enhanced recovery stem-cell transplantation: multidisciplinary efforts to improve outcomes in older adults undergoing hematopoietic stem-cell transplant

A Ngo-Huang, R Ombres, RM Saliba… - JCO oncology …, 2023 - ascopubs.org
PURPOSE: Older adults have unique risk factors for poor outcomes after hematopoietic stem-
cell transplant (HSCT). We sought to determine the impact of our multidisciplinary supportive …

Health-related quality of life in young adult survivors of hematopoietic cell transplantation

SJ Rotz, CY Jean, BK Hamilton, W Wei… - … and cellular therapy, 2022 - Elsevier
ABSTRACT Young adults (YA), age 18 to 39 years, are at a stage of life that may make them
more vulnerable than older adults to impairments in health-related quality of life (HRQOL) …

[HTML][HTML] Challenges and potential solutions for recruitment and retention of hematopoietic cell transplantation physicians: the National Marrow Donor Program's …

LJ Burns, JL Gajewski, NS Majhail, W Navarro… - Biology of Blood and …, 2014 - Elsevier
Hematopoietic cell transplantation (HCT) remains the only known curative therapy for many
patients with hematologic, metabolic, and immunologic disorders. Furthermore, the use of …

Comorbidities, age, and other patient-related predictors of allogeneic hematopoietic cell transplantation outcomes

V Wais, D Bunjes, F Kuchenbauer… - Expert Review of …, 2018 - Taylor & Francis
Introduction: Allogeneic hematopoietic cell transplantation (HCT) provides potential cure to a
large number of malignant and nonmalignant hematological disorders. With the …