The goal of this review is to provide further understanding of increased vascular stiffness
with aging, and how it contributes to the adverse effects of major human diseases …

The growing prevalence and associated risk of arterial stiffness provide a major challenge to
better understand the underlying causes and the resultant physiological impact of this …

In recent decades, the pervasiveness of increased arterial stiffness in patients with
cardiovascular disease has become increasingly apparent. Though, this phenomenon has …

Arterial stiffness is a growing epidemic associated with increased risk of cardiovascular
events, dementia, and death. Decreased compliance of the central vasculature alters arterial …

Large elastic artery stiffness is an independent predictor of age-related cardiovascular
events that is attributable to structural remodeling throughout the artery. The intima, media …

Arterial stiffness results from a degenerative process affecting mainly the extracellular matrix
of elastic arteries under the effect of aging and risk factors. Changes in extracellular matrix …

Aging is the dominant process altering vascular stiffness. Risk factors for cardiovascular
disease, such as smoking, hypertension and diabetes mellitus, mediate their effects by …

Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

BACKGROUND Vascular age is an emerging health indicator and predictor of end-organ
damage to the heart, brain, and kidney. Although there have been many review publications …

Background—Our hypothesis was that the changes in vascular properties responsible for
aortic stiffness with aging would be greater in old male monkeys than old female monkeys …