[HTML][HTML] Altered Morpho-Functional Features of Neurogenesis in Zebrafish Embryos Exposed to Non-Combustion-Derived Magnetite

P Cacialli, S Ricci, GP Servetto, V Franceschini… - International Journal of …, 2024 - mdpi.com
Neurogenesis is the process by which new brain cells are formed. This crucial event
emerges during embryonic life and proceeds in adulthood, and it could be influenced by …

Long-term effects of nanoscale magnetite on human forebrain-like tissue development in stem-cell-derived cortical spheroids

ED Henderson, T Hua, S Kiran, ZI Khamis… - ACS Biomaterials …, 2022 - ACS Publications
The environmental nanoscale iron magnetite may contribute to the risk of developing
neurodegenerative diseases. In addition, iron oxides can be used as the contrast agents in …

Single-cell transcriptomics analysis of zebrafish brain reveals adverse effects of manganese on neurogenesis

X Wang, X Yang, W He, S Zhang, X Song, J Zhang… - Environmental …, 2024 - Elsevier
Manganese (Mn) is considered as an important environmental risk factor for Parkinson's
disease. Excessive exposure to Mn can damage various neural cells and affect the …

Comparative transcriptomics revealed neurodevelopmental impairments and ferroptosis induced by extremely small iron oxide nanoparticles

Z Lyu, Y Kou, Y Fu, Y Xie, B Yang, H Zhu… - Frontiers in Genetics, 2024 - frontiersin.org
Iron oxide nanoparticles are a type of nanomaterial composed of iron oxide (Fe3O4 or
Fe2O3) and have a wide range of applications in magnetic resonance imaging. Compared …

Evaluation of Magnetite Nanoparticle-Based Toxicity on Embryo–Larvae Stages of Zebrafish (Danio rerio)

A Jurewicz, S Ilyas, JK Uppal, I Ivandic… - ACS Applied Nano …, 2020 - ACS Publications
Iron oxide nanoparticles (NPs) are extensively used in various biomedical applications due
to their suitability as carriers of diagnostic and therapeutic agents. Herein, we report on the …

[HTML][HTML] Developmental neurotoxicity screening for nanoparticles using neuron-like cells of human umbilical cord mesenchymal stem cells: example with magnetite …

T Coccini, P Pignatti, A Spinillo, U De Simone - Nanomaterials, 2020 - mdpi.com
Metallic nanoparticles (NPs), as iron oxide NPs, accumulate in organs, cross the blood-brain
barrier and placenta, and have the potential to elicit developmental neurotoxicity (DNT) …

[HTML][HTML] The Threat Posed by Environmental Contaminants on Neurodevelopment: What Can We Learn from Neural Stem Cells?

R Bose, S Spulber, S Ceccatelli - International Journal of Molecular …, 2023 - mdpi.com
Exposure to chemicals may pose a greater risk to vulnerable groups, including pregnant
women, fetuses, and children, that may lead to diseases linked to the toxicants' target …

Evaluation of maghemite nanoparticles–induced developmental toxicity and oxidative stress in zebrafish embryos/larvae

NA Thirumurthi, A Raghunath… - … Trace Element Research, 2022 - Springer
Abstract Maghemite nanoparticles (Fe _ 2 O _ 3 Fe 2 O 3 NPs) have a wide array of
applications in various industries including biomedical field. There is an absence of …

Cytotoxicity and proliferative capacity impairment induced on human brain cell cultures after short‐and long‐term exposure to magnetite nanoparticles

T Coccini, F Caloni, LJ Ramirez Cando… - Journal of Applied …, 2017 - Wiley Online Library
Since magnetic iron oxide nanoparticles (IONP) as magnetite (Fe3O4NPs) have potential
applications in life sciences, industrial fields and biomedical care, the risks for occupational …

[HTML][HTML] Neuron-like cells generated from human umbilical cord lining-derived mesenchymal stem cells as a new in vitro model for neuronal toxicity screening: using …

U De Simone, A Spinillo, F Caloni, L Gribaldo… - International journal of …, 2019 - mdpi.com
The wide employment of iron nanoparticles in environmental and occupational settings
underlines their potential to enter the brain. Human cell-based systems are recommended …